Dr. David Hendrix, PhD
Dept. of Biochemistry and Biophysics
School of Electrical Engineering and Computer Science
Oregon State University, Corvallis, OR, USA
Hangout Title:"Biological discovery through Transcriptomics"
Hangout Schedule:June 1st 2017: 2 pm PST, 4 pm CST, 5 pm EST
B.S. Applied Mathematics, B.S Physics, Georgia Institute of Technology
Ph.D. Physics, University of California, Berkeley
Postdoc, University of California, Berkeley
Postdoc, Massachusetts Institute of Technology CSAIL
CS 419 (Section 001) ST/ALGRTHMS F/COMP MOLEC BIO
CS 519 (Section 002) ST/ ALGRTHMS F/COMP MOLEC BIO
The primary focus of our lab is to understand the structure, function and mechanisms of action of non-coding RNAs, both large and small. The past decade has seen the discovery of numerous non-coding RNAs whose function is largely unknown. We will employ structure prediction, genome-wide sequence analysis and deep sequencing data to uncover the roles of these molecules in gene regulation.
In addition, our lab develops algorithms and computational approaches to understand many different areas of computational biology. Our lab develops and utilizes motif finding algorithms to understand how promoters and regulatory elements operate. We develop computational approaches, incorporating structural predictions and deep sequencing data, to discover new regulatory RNAs and their functions. We develop new methods of analysis for deep sequencing data to help understand the principles of transcription, which will include transcription initiation, transcriptional gene silencing, post-transcriptional gene silencing and Polymerase stalling/pausing.