There are important differences in how individuals approach life. While some people are relaxed and calm, others often see situations as threatening, making them worried and tense. This kind of “trait” anxiety has significant consequences on a person’s social life, undermining their confidence to compete for social standing

In our competitive world, high-anxious individuals have a disadvantage and can feel overlooked and rejected; as a result this can lead to what psychologists call “social subordination”.

 Publishing in PNAS, neuroscientists at EPFL have pinpointed an area of the brain related to motivation and depression that could link trait anxiety to social subordination.

The researchers performed a series of experiments to identify the brain areas involved in trait anxiety and social competition. The experiments involved categorizing rats on a spectrum of trait anxiety, from low-anxious to high-anxious rats, which model trait anxiety.

The animals underwent several behavioral tests that required high-anxious rats to compete socially with their low-anxious counterparts, and their performance was quantified and analyzed statistically. In addition, the researchers examined the brains of the rats to identify changes in biological function.

The experiments highlighted an area of the brain known as the “nucleus accumbens”, which has been long-associated with motivation, reward and depression – in humans too. When competing socially, most of the high-anxious rats took on a lower social status – technically described as becoming “socially subordinate”.

The nucleus accumbens of these particular rats showed a reduced energy metabolism. This involves the mitochondria, which are the cell’s organelles that are in charge of breathing and energy production. The researchers found that the high-anxious rats showed lower mitochondrial function than more relaxed ones.

The scientists confirmed their findings with pharmacological manipulation: they gave the nucleus accumbens of rats drugs that either block or enhance mitochondria – one of the drugs was a part of the common vitamin B3 (niacin). When rats received blocking agents, their social competitiveness dropped, taking their social status with it.

On the other hand, when high-anxious rats were given enhancers, rats performed significantly better socially, thereby achieving higher social status. But the effects were not permanent: when the drugs wore off, the rats generally returned to their original rung of the social ladder.

The study confirms that trait anxiety can actually predispose an individual to a lower social status. This could mean that pharmacological manipulation of mitochondria in the nucleus accumbens could potentially influence the social rank of a person. The study is also the first to relate that brain energy metabolism influences the establishment of social hierarchies.

Author remains cautious, since the study involved rats rather than humans; after all, brain function is just one of the many elements that influence social dynamics.

http://actu.epfl.ch/news/anxiety-can-kill-your-social-status/