Researchers found that chronic alcohol consumption has a dramatic effect on the way the body handles vitamin A.
Researchers analyzed the liver and other organs (i.e., kidney, spleen, heart, lung, white adipose, brown adipose and blood), from mice fed with alcohol-containing food and alcohol-free food and measured tissue vitamin A levels.
The alcohol-fed mice had distinct changes in how their body handled vitamin A. In general, vitamin A levels were lower in the liver and higher in other tissues. This strongly suggests that vitamin A in the liver is reduced by excessive alcohol consumption and that these findings are important in the development of alcoholic liver disease.