Gut microbiomes can influence the effectiveness of dietary treatments

Gut microbiomes can influence the effectiveness of dietary treatments
 

Previous studies at the have shown that the gut microbiota is altered in metabolic diseases such as type 2 diabetes, and that the gut microbiota contributes to obesity, diabetes and cardiovascular disease.

A new study, published in Cell Metabolism, shows that people with better control of blood sugar after eating barley kernel bread also have a different balance of microbes in the gut.

In a new study, 39 subjects ate barley kernel bread for three days followed by control bread made from white flour for three days (with a break between the two diets). The results showed that barley kernel bread improved the control of blood sugar, but only in some individuals.

Prevotella, a group of bacteria previously shown to be associated with high fiber intake, was present in higher proportions in those who responded beneficially to barley kernel bread than in those who did not respond to this dietary intervention.

By transferring the gut microbiota of these individuals to germ-free mice, the research group could demonstrate that the altered gut microbiota contributed to the beneficial effects of the barley kernel bread.

The researchers are now planning further studies and hope to confirm if the gut microbiota can identify which individuals will respond to a specific diet.

http://sahlgrenska.gu.se/english/research/news-article/?languageId=100001&contentId=1332489&disableRedirect=true&returnUrl=http%3A%2F%2Fsahlgrenska.gu.se%2Fforskning%2Fnyhet%2F%2Ftarmfloran-kan-paverka-effekten-av-dieter.cid1332489

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