'Gut' bacteria may help put a kink in family obesity cycle

'Gut' bacteria may help put a kink in family obesity cycle

Obesity is a global epidemic and the evidence is clear: if a mother is obese or gains too much weight during pregnancy chances are the child will be at higher risk of being obese throughout its life.

A new animal study, published in Scientific Reports, reveals insight on how a special type of dietary fibre, known as prebiotic, impacts the mother's gut microbiota and may be one factor in curbing obesity in moms and their babies.

People are most familiar with probiotics which are live bacteria that can be found in a variety of food, including yoghurt and sauerkraut, and they aid in digestive health. Prebiotics, not a household name, are used in this study. Prebiotics are a form of dietary fibre, which are found naturally in garlic, onions, bananas and whole wheat. They are non-digestible food which pass into the lower gastrointestinal tract where they stimulate, actually feed, the growth of health-promoting bacteria.

For this study, a prebiotic supplement was given to rats on a high-fat and high-sugar diet during their three-week pregnancy and three-weeks post-birth, during lactation. The rats taking the supplement ate less, and both baby and mother had a lower percentage of body fat - 33 percent for mom and 30 per cent for newborn - compared to the rats that ate the same diet but with no supplement.

"We know from previous studies we have done in humans that prebiotics can reduce hunger and make you feel fuller. We determined this was because of an increase in two hormones which triggered satiety," says the author. "We saw these same 'fullness' hormones increase in our pregnant rats when they ate the prebiotic. What was most important was that by mom improving the bacteria profile in her gut, that healthy gut microbiota profile was transferred to the baby."

The magnitude of the effect would be different in humans, author cautions. "The prebiotics worked beautifully to reduce weight gain and lower-fat mass in the rats; however, a person is far more complex. In the rat study we could very closely control their diet but in real life there are many other triggers that may contribute to obesity, including genetics, environment and mental health. Prebiotics are one tool to help with weight management but they are not a cure for obesity."

All parents want healthy babies. Author says there are some excellent resources to help mothers navigate what to do for a healthy pregnancy.

http://www.ucalgary.ca/utoday/issue/2016-03-02/eating-more-prebiotics-during-pregnancy-may-reduce-obesity-babies

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