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Beta cells intrinsically sense and limit their secretory activity via mTORC1-RhoA signaling

Beta cells intrinsically sense and limit thei...

 0

Circulating glycerate predicts resilience to fructose- induced hepatic steatosis

Circulating glycerate predicts resilience to ...

 9

Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures

Divergent actions of physiological and pathol...

 10

Antiviral discovery using sparse datasets by integrating experiments, molecular simulations, and machine learning

Antiviral discovery using sparse datasets by ...

 14

Beta cells intrinsically sense and limit their secretory activity via mTORC1-RhoA signaling

Beta cells intrinsically sense and limit thei...

 0

Circulating glycerate predicts resilience to fructose- induced hepatic steatosis

Circulating glycerate predicts resilience to ...

 9

Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures

Divergent actions of physiological and pathol...

 10

Antiviral discovery using sparse datasets by integrating experiments, molecular simulations, and machine learning

Antiviral discovery using sparse datasets by ...

 14

Minimally invasive, wide-field two-photon imaging of the brainstem at cellular resolution

Minimally invasive, wide-field two-photon ima...

 25

Quantitative PET imaging and modeling of molecular blood-brain barrier permeability

Quantitative PET imaging and modeling of mole...

 33

Species-resolved profiling of antibiotic resistance genes in complex metagenomes through long-read overlapping with Argo

Species-resolved profiling of antibiotic resi...

 53

Integrated analysis of transcriptional and metabolic responses to mitochondrial stress

Integrated analysis of transcriptional and me...

 64

Protein Digestion and Absorption

Protein Digestion and Absorption

 480

AlphaFold: for Protein Structure Prediction

AlphaFold: for Protein Structure Prediction

 132

Protein structure, classification, functions, properties of proteins

Protein structure, classification, functions,...

 223

Post Translation Modification

Post Translation Modification

 257

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGET...

 5949

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

 302

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

 303

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

 317

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Science Hangouts

Protein monoaminylation in brain: novel mechanisms of neural development, plasticity and disease
Science Hangouts

Protein monoaminylation in brain: novel mechanisms of neural development, plasticity and disease

 18663

Dynamics of  muscle stem cells in skeletal muscle homeostasis and repair
Science Hangouts

Dynamics of muscle stem cells in skeletal muscle homeostasis and repair

 259

The Science of Exercise
Science Hangouts

The Science of Exercise

 234

Cancer, Inflammation & Tissue Repair
Science Hangouts

Cancer, Inflammation & Tissue Repair

 222

Deubiquitinases in cell cycle and cancer
Science Hangouts

Deubiquitinases in cell cycle and cancer

 213

Circadian Rhythms, Nutrition and Metabolism
Science Hangouts

Circadian Rhythms, Nutrition and Metabolism

 274

Local Translation and Generation of Novel Protein Isoforms in Astrocytes
Science Hangouts

Local Translation and Generation of Novel Protein Isoforms in Astrocytes

 246

Digestive Enzymes On the Loose: Autodigestion in Metabolic Disease, Shock and Death
Science Hangouts

Digestive Enzymes On the Loose: Autodigestion in Metabolic Disease, Shock and Death

 404

Targeting integrins with small molecules to cure cancer and lupus
Science Hangouts

Targeting integrins with small molecules to cure cancer and lupus

 283

Pain and Self-Fulfilling Prophesies
Science Hangouts

Pain and Self-Fulfilling Prophesies

 307

Science News Highlights

Predicting resilience to fructose induced hepatic steatosis
News highlights

Predicting resilience to fructose induced hepatic steatosis

 3

Plant breeding using rhizosphere microbiome biodiversity
News highlights

Plant breeding using rhizosphere microbiome biodiversity

 9

Neuromelanin and  Parkinson’s disease
News highlights

Neuromelanin and Parkinson’s disease

 11

News

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Interplay between human genetics and intratumoral microbiota in colorectal cancer

Interplay between human genetics and intratumoral ...

 13

Role of physiological and pathological Aβ on synapses in human brain tissue

Role of physiological and pathological Aβ on synap...

 26

AI uncovers antiviral compounds using limited data!

AI uncovers antiviral compounds using limited data!

 40

Clusterin protein alleviates Alzheimer’s disease-relevant processes

Clusterin protein alleviates Alzheimer’s disease-r...

 64

How brain weighs positive vs. negative social experience?

How brain weighs positive vs. negative social expe...

 131

Eliminating excessive scarring during wound healing

Eliminating excessive scarring during wound healing

 55

Innovative deep-brain imaging to study brainstem structures

Innovative deep-brain imaging to study brainstem s...

 79

Broadly neutralizing human antibodies to neutralize snake venom

Broadly neutralizing human antibodies to neutraliz...

 39

Lactate links metabolism and epigenetics for trained immunity

Lactate links metabolism and epigenetics for train...

 71

Temperature-controlled calcium channel, CatSper activates sperm

Temperature-controlled calcium channel, CatSper ac...

 38

Ferroptosis induction by lysosomal lipid peroxidation

Ferroptosis induction by lysosomal lipid peroxidation

 120

Mechanism governing specific binding of EVs to recipient cells

Mechanism governing specific binding of EVs to rec...

 63

Circulating miR-126-3p is a biomarker for knee osteoarthritis

Circulating miR-126-3p is a biomarker for knee ost...

 51

Role of physiological and pathological Aβ on synapses in human brain tissue

Role of physiological and pathological Aβ on synap...

 26

Clusterin protein alleviates Alzheimer’s disease-relevant processes

Clusterin protein alleviates Alzheimer’s disease-r...

 64

How brain weighs positive vs. negative social experience?

How brain weighs positive vs. negative social expe...

 131

Connection between autism spectrum disorder and myotonic dystrophy

Connection between autism spectrum disorder and my...

 38

Adolescents who sleep longer perform better at cognitive tasks

Adolescents who sleep longer perform better at cog...

 105

Why can’t we have childhood memories?

Why can’t we have childhood memories?

 91

Mice exhibit altruistic rescue behavior driven by oxytocin

Mice exhibit altruistic rescue behavior driven by ...

 41

Misfolded alpha-synuclein protein as diagnostic biomarker for PD

Misfolded alpha-synuclein protein as diagnostic bi...

 62

A gut-brain link that may affect behavior in children with autism

A gut-brain link that may affect behavior in child...

 355

LSD analogue with potential for treating schizophrenia

LSD analogue with potential for treating schizophr...

 212

What happens in the brain when your mind blanks

What happens in the brain when your mind blanks

 157

Enzymes critical for astrocytic GABA production in Alzheimer’s disease identified!

Enzymes critical for astrocytic GABA production in...

 179

Stopping mitochondrial fusion to prevent escape of mitochondrial DNA

Stopping mitochondrial fusion to prevent escape of...

 118

Interplay between human genetics and intratumoral microbiota in colorectal cancer

Interplay between human genetics and intratumoral ...

 13

Ferroptosis induction by lysosomal lipid peroxidation

Ferroptosis induction by lysosomal lipid peroxidation

 120

Three-dimensional gene hubs may promote brain cancer

Three-dimensional gene hubs may promote brain cancer

 23

Targeting PIKfyve-driven lipid metabolism in pancreatic cancer

Targeting PIKfyve-driven lipid metabolism in pancr...

 48

Linking germline variants to cancer progression

Linking germline variants to cancer progression

 33

Tumor-derived erythropoietin acts as an immunosuppressive switch in cancer immunity

Tumor-derived erythropoietin acts as an immunosupp...

 111

Gut microbes release cancer-fighting bile acids that block hormone signals

Gut microbes release cancer-fighting bile acids th...

 172

CD36-dependent pathway to enhance cancer drug uptake

CD36-dependent pathway to enhance cancer drug uptake

 50

Gene fusion may cause explosive growth in chronic myeloid leukaemia

Gene fusion may cause explosive growth in chronic ...

 65

Lysosomal dysfunction strategy to treat glioblastoma

Lysosomal dysfunction strategy to treat glioblastoma

 81

How aspirin could prevent some cancers from spreading

How aspirin could prevent some cancers from spreading

 132

Designer bacteria for cancer therapy

Designer bacteria for cancer therapy

 289

Gene expression programs in immune cells from glioma tumors identified!

Gene expression programs in immune cells from glio...

 87

Tirzepatide's role in weight loss and metabolic health

Tirzepatide's role in weight loss and metabolic he...

 46

How molecular glues protect insulin-producing cells from diabetic damage

How molecular glues protect insulin-producing cell...

 116

Dramatic changes in liver metabolism during fasting

Dramatic changes in liver metabolism during fasting

 211

Obesity gene in dogs is also relevant to humans

Obesity gene in dogs is also relevant to humans

 131

Blood vessel inflammation from artificial sweetener

Blood vessel inflammation from artificial sweetener

 146

Adipose populations linked to metabolic health in obesity

Adipose populations linked to metabolic health in ...

 129

A light-sensitive brain protein, opsin 3, also regulates food consumption

A light-sensitive brain protein, opsin 3, also reg...

 158

Intermittent fasting could be unsafe for teenagers

Intermittent fasting could be unsafe for teenagers

 148

Mechanism of endothelial insulin resistance

Mechanism of endothelial insulin resistance

 153

Gut microbes link drinking sugary beverages and diabetes risk

Gut microbes link drinking sugary beverages and di...

 170

A ‘non-industrialized’ style diet can reduce risk of chronic disease

A ‘non-industrialized’ style diet can reduce risk ...

 153

Multi-omics identifies risk factors of childhood obesity

Multi-omics identifies risk factors of childhood o...

 147

Microbial regulation of bile acid signalling

Microbial regulation of bile acid signalling

 155

AI uncovers antiviral compounds using limited data!

AI uncovers antiviral compounds using limited data!

 40

AI identifies PHGDH as amyloid pathology driver in Alzheimer’s disease

AI identifies PHGDH as amyloid pathology driver in...

 120

AI tool to better assess Parkinson’s disease, other movement disorders

AI tool to better assess Parkinson’s disease, othe...

 51

AI tool can track effectiveness of multiple sclerosis treatments

AI tool can track effectiveness of multiple sclero...

 52

AI to improve diagnosis of drug-resistant infections

AI to improve diagnosis of drug-resistant infections

 71

AI models of the brain could serve as ‘digital twins’ in research

AI models of the brain could serve as ‘digital twi...

 104

Pain relief with designer cannabinoids without adverse effects

Pain relief with designer cannabinoids without adv...

 111

Newly discovered weight loss peptide without side effects

Newly discovered weight loss peptide without side ...

 291

Automatic cell analysis using AI

Automatic cell analysis using AI

 97

Deep learning to quantify the pace of brain aging

Deep learning to quantify the pace of brain aging

 139

Machine learning of B cell and T cell receptor sequences for disease diagnostics

Machine learning of B cell and T cell receptor seq...

 100

Memory’s hidden architecture uncovered!

Memory’s hidden architecture uncovered!

 260

AI predicts hepatocellular carcinoma recurrence

AI predicts hepatocellular carcinoma recurrence

 164

New lipid nanoparticle platform delivers mRNA to the brain through the blood-brain barrier

New lipid nanoparticle platform delivers mRNA to t...

 188

Microfluidic protocol to extract and purify DNA

Microfluidic protocol to extract and purify DNA

 102

Artificial sensing system using synthetic neurons

Artificial sensing system using synthetic neurons

 158

The nanoparticle-based vaccine against many variants of SARS-CoV-2

The nanoparticle-based vaccine against many varian...

 109

Nanoparticle-based itaconate treatment for atherosclerotic plaque resolution

Nanoparticle-based itaconate treatment for atheros...

 137

A lipid nanoparticle delivers mRNA cure for pre-eclampsia

A lipid nanoparticle delivers mRNA cure for pre-ec...

 137

‘Supercharging’ T cells with mitochondria enhances their antitumor activity

‘Supercharging’ T cells with mitochondria enhances...

 143

Can we ‘recharge’ our cells?

Can we ‘recharge’ our cells?

 155

How can alterations in metabolism encode specific transcriptional instructions

How can alterations in metabolism encode specific t...

 48

Growing chimpanzee naive-type pluripotent stem cells for the first time

Growing chimpanzee naive-type pluripotent stem cel...

 101

Aging-related blood disorders from supercharged mitochondria

Aging-related blood disorders from supercharged mi...

 70

New neurons may reverse damage in Huntington’s disease

New neurons may reverse damage in Huntington’s dis...

 67

Placenta-derived factor promotes the expansion of liver progenitor cells

Placenta-derived factor promotes the expansion of ...

 52

Human assembloid model of the ascending neural sensory pathway

Human assembloid model of the ascending neural sen...

 50

How gut cells respond to bacterial toxins

How gut cells respond to bacterial toxins

 240

Mechanisms of aging in Meibomian gland

Mechanisms of aging in Meibomian gland

 113

Stem cells based circadian drug delivery

Stem cells based circadian drug delivery

 110

How healthy stem cells turn into oral cancer

How healthy stem cells turn into oral cancer

 93

Lifelong maintenance of intestinal stem cells

Lifelong maintenance of intestinal stem cells

 95

How neural stem cells are activated in the adult human brain

How neural stem cells are activated in the adult h...

 122

The maternal microbiome during pregnancy impacts offspring’s stem cells in mice

The maternal microbiome during pregnancy impacts o...

 138

ITSN1 gene linked to substantial risk of Parkinson’s disease

ITSN1 gene linked to substantial risk of Parkinson...

 101

Disordered renal metabolism in myotonic dystrophy type 1

Disordered renal metabolism in myotonic dystrophy ...

 100

Gene ‘silencer’ in junk DNA prevents fatal neurological disease

Gene ‘silencer’ in junk DNA prevents fatal neurolo...

 79

The role of moms X chromosome in cognition and aging of daughter

The role of moms X chromosome in cognition and agi...

 85

Genes for depression across ethnicities

Genes for depression across ethnicities

 97

Gene editing extends lifespan in mouse model of prion disease

Gene editing extends lifespan in mouse model of pr...

 93

Two new gene variants linked to epilepsy identified!

Two new gene variants linked to epilepsy identified!

 120

Dysregulation of mTOR signalling is a converging mechanism in lissencephaly

Dysregulation of mTOR signalling is a converging m...

 120

The role of rare germline structural variants in pediatric solid tumors

The role of rare germline structural variants in p...

 109

Linking genetic risk for schizophrenia to a malformed skull

Linking genetic risk for schizophrenia to a malfor...

 100

New mutation linked to early-onset Parkinsonism

New mutation linked to early-onset Parkinsonism

 123

Combination therapy to treat glioma

Combination therapy to treat glioma

 106

How unique metabolism protects naked mole rats from heart attacks

How unique metabolism protects naked mole rats fro...

 110

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

 134

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

 118

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

 118

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

 129

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

 116

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

 117

Role of ECM in brain memory

Role of ECM in brain memory

 110

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

 119

Supramolecular anticoagulants with on-demand reversibility

Supramolecular anticoagulants with on-demand rever...

 124

Cell vulnerability 'fingerprint' related to Parkinson's identified!

Cell vulnerability 'fingerprint' related to Parkin...

 120

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

 119

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

 109

Gut bacteria produced compounds can treat inflammation

Gut bacteria produced compounds can treat inflamma...

 112

TMEM65 regulates mitochondrial calcium efflux

TMEM65 regulates mitochondrial calcium efflux

 57

Inhibition of ceramide synthesis contributes to cardiometabolic diseases

Inhibition of ceramide synthesis contributes to ca...

 53

How a Y chromosome gene may shape the course of heart valve disease

How a Y chromosome gene may shape the course of he...

 169

Why babies recover, but adults scar, after heart damage

Why babies recover, but adults scar, after heart d...

 87

Testosterone increases damage following a heart attack

Testosterone increases damage following a heart at...

 89

The structure of apolipoprotein B100 from human low-density lipoprotein

The structure of apolipoprotein B100 from human lo...

 101

Blood vessel lumen formation and maintenance

Blood vessel lumen formation and maintenance

 121

First noninvasive method to continually measure true blood pressure

First noninvasive method to continually measure tr...

 119

A glutamine metabolic switch in red blood cell development and disease

A glutamine metabolic switch in red blood cell dev...

 140

Protein kinase N promotes cardiac fibrosis in heart failure

Protein kinase N promotes cardiac fibrosis in hear...

 122

Role of lipids in regulating cardiac arrhythmias

Role of lipids in regulating cardiac arrhythmias

 161

Temperature-controlled calcium channel, CatSper activates sperm

Temperature-controlled calcium channel, CatSper ac...

 38

How mothers adapt to the metabolic demands of nursing

How mothers adapt to the metabolic demands of nursing

 48

A protein complex critical to male fertility uncovered!

A protein complex critical to male fertility uncov...

 80

Association between placental DNA methylation and schizophrenia

Association between placental DNA methylation and ...

 449

Interactions between sex hormones and neurological health

Interactions between sex hormones and neurological...

 134

Cell-free DNA shed from the placenta during pregnancy predicts preeclampsia

Cell-free DNA shed from the placenta during pregna...

 108

Communication between body muscle and the brain influences fertility

Communication between body muscle and the brain in...

 111

Epigenetic programming in uterine fibroblasts regulate birth timing

Epigenetic programming in uterine fibroblasts regu...

 89

Grey matter (94%) in the brains of mothers undergoes changes during pregnancy

Grey matter (94%) in the brains of mothers undergo...

 101

Surges in estrogen promotes binge drinking in females

Surges in estrogen promotes binge drinking in females

 105

Extra X chromosome impairs the development of male fetal germ cells

Extra X chromosome impairs the development of male...

 118

Mothers massively change their intestines during pregnancy and nursing

Mothers massively change their intestines during p...

 135

A key transcription factor modulates expanded pluripotency in blastoids and blastocysts

A key transcription factor modulates expanded plur...

 113

Eliminating excessive scarring during wound healing

Eliminating excessive scarring during wound healing

 55

Mechanism governing specific binding of EVs to recipient cells

Mechanism governing specific binding of EVs to rec...

 63

Circulating miR-126-3p is a biomarker for knee osteoarthritis

Circulating miR-126-3p is a biomarker for knee ost...

 51

Synthetic lethal interactions among DNA repair factors

Synthetic lethal interactions among DNA repair fac...

 38

Tool to analyze protein turnover in a single cell

Tool to analyze protein turnover in a single cell

 43

Fetal anemia linked to mitochondrial protein synthesis deficiency

Fetal anemia linked to mitochondrial protein synth...

 104

Small molecules restore mutant mitochondrial DNA polymerase activity

Small molecules restore mutant mitochondrial DNA p...

 77

Engineering smart delivery for gene editors

Engineering smart delivery for gene editors

 87

Improved method for producing designer proteins

Improved method for producing designer proteins

 114

New mechanism to relieve mitochondrial stress

New mechanism to relieve mitochondrial stress

 136

Tracking material carried by extracellular vesicles (EVs)

Tracking material carried by extracellular vesicle...

 73

Circadian rhythms affect muscle repair

Circadian rhythms affect muscle repair

 134

Structural insight into DNA’s unwinding mechanism

Structural insight into DNA’s unwinding mechanism

 117

A symbiotic gut fungus wards off liver disease in mice

A symbiotic gut fungus wards off liver disease in ...

 33

Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis

Nerve- and airway-associated interstitial macropha...

 77

First structural images of a tuberculosis-fighting virus

First structural images of a tuberculosis-fighting...

 78

Tool for tracking antibiotic resistance genes

Tool for tracking antibiotic resistance genes

 214

Brain linked stress and satiety modulators in pathogen infection induced sickness behaviors

Brain linked stress and satiety modulators in path...

 59

Fiber consumption protects gut from serious bacterial infection

Fiber consumption protects gut from serious bacter...

 128

Mechanisms underlying antiviral immunity against phages

Mechanisms underlying antiviral immunity against p...

 102

Intestinal immune cell prevents food allergies

Intestinal immune cell prevents food allergies

 127

Cellular regulator of mRNA vaccine revealed!

Cellular regulator of mRNA vaccine revealed!

 151

Attenuated Mycobacterium tuberculosis vaccine candidate to prevent tuberculosis

Attenuated Mycobacterium tuberculosis vaccine cand...

 73

Regeneration of macrophage peroxisomes limit SARS-CoV-2 tissue inflammation

Regeneration of macrophage peroxisomes limit SARS-...

 159

COVID-19 neuro-inflammation from microglia dysfunction, neurovascular inflammation and focal neuropathologies

COVID-19 neuro-inflammation from microglia dysfunc...

 860

Inhibiting bacterial gene translation using siRNA

Inhibiting bacterial gene translation using siRNA

 93

MicroRNAs guide the development of Purkinje cells

MicroRNAs guide the development of Purkinje cells

 127

Ancient viral DNA shapes early embryo development

Ancient viral DNA shapes early embryo development

 81

Mechanism to bring newborn neurons out of the neuronal nest

Mechanism to bring newborn neurons out of the neur...

 103

Leptin in neurodevelopment!

Leptin in neurodevelopment!

 114

Role of Integrator in early neural fate commitment

Role of Integrator in early neural fate commitment

 133

Impaired chaperonin function may cause brain malformations and seizures

Impaired chaperonin function may cause brain malfo...

 132

Role of protein netrin1 in spinal cord development

Role of protein netrin1 in spinal cord development

 122

Inhibiting metabolic enzyme to “pause" human development

Inhibiting metabolic enzyme to “pause" human devel...

 127

Human-specific genes regulate key gene mutated in autism spectrum disorders

Human-specific genes regulate key gene mutated in ...

 117

Physiological role of 5-formylcytosine (5fC) epigenetic marker in the embryonic development

Physiological role of 5-formylcytosine (5fC) epige...

 117

Plant-based protein is linked to a longer life

Plant-based protein is linked to a longer life

 47

Epigenetic marker is essential for Marchantia sperm function

Epigenetic marker is essential for Marchantia sper...

 69

Anti-bacterial role of plant metabolite

Anti-bacterial role of plant metabolite

 97

Key genes to fight against crop parasites identified!

Key genes to fight against crop parasites identified!

 72

CoQ10-producing rice with gene editing

CoQ10-producing rice with gene editing

 84

Bacteria used to amplify plant hormones

Bacteria used to amplify plant hormones

 88

Protein protects biological nitrogen fixation from oxidative stress

Protein protects biological nitrogen fixation from...

 92

Plant roots change their growth pattern during ‘puberty’

Plant roots change their growth pattern during ‘pu...

 124

The biosynthesis of steroidal defense metabolites in plants

The biosynthesis of steroidal defense metabolites ...

 123

Decoding plant-to-fungi communication

Decoding plant-to-fungi communication

 126

Stopping plants from passing viruses to their progeny

Stopping plants from passing viruses to their progeny

 118

How female gametes control fertilization recovery in flowering plants

How female gametes control fertilization recovery ...

 123

How plants pass down genetic memories

How plants pass down genetic memories

 110

Broadly neutralizing human antibodies to neutralize snake venom

Broadly neutralizing human antibodies to neutraliz...

 39

Lactate links metabolism and epigenetics for trained immunity

Lactate links metabolism and epigenetics for train...

 71

Predicting relapse of autoimmune small vessel vasculitis

Predicting relapse of autoimmune small vessel vasc...

 86

Asian Immune Diversity Atlas

Asian Immune Diversity Atlas

 28

Acetylcholine structure reveals mechanisms that cause autoimmune disease

Acetylcholine structure reveals mechanisms that ca...

 94

Peacekeeper cells protect the body from autoimmunity during infection

Peacekeeper cells protect the body from autoimmuni...

 204

Ginger compound with potential to treat inflammatory bowel disease

Ginger compound with potential to treat inflammato...

 102

Intercellular mRNA transfer alters the human pluripotent stem cell state

Intercellular mRNA transfer alters the human pluri...

 82

A treatment-resistant, severe type of asthma successfully modeled in mice

A treatment-resistant, severe type of asthma succe...

 76

How Tregs control the immune system

How Tregs control the immune system

 99

Opioid delta-receptor agonists alleviate stress-induced irritable bowel syndrome symptoms

Opioid delta-receptor agonists alleviate stress-in...

 77

Activation of the entire complement cascade in inflammatory and autoimmune diseases

Activation of the entire complement cascade in inf...

 92

Tailoring immunotherapies for childhood cancers

Tailoring immunotherapies for childhood cancers

 86

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

 44

Printed skin to replace animal testing

Printed skin to replace animal testing

 59

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

 71

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

 81

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

 92

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

 120

Innovative deep-brain imaging to study brainstem structures

Innovative deep-brain imaging to study brainstem s...

 79

RNA blood test to detect cancers

RNA blood test to detect cancers

 73

EXPLORER total body PET scanner may help detect brain disease

EXPLORER total body PET scanner may help detect br...

 41

Simulating multilayered protein condensates support learning and memory

Simulating multilayered protein condensates suppor...

 55

Structural insight into mitochondrial pyruvate carrier

Structural insight into mitochondrial pyruvate car...

 63

Cell membranes sustain phospholipid imbalance via cholesterol asymmetry

Cell membranes sustain phospholipid imbalance via ...

 207

Nonlinear sound-sheet microscopy

Nonlinear sound-sheet microscopy

 55

Hearing triggered by molecular “spring”

Hearing triggered by molecular “spring”

 63

“Ball and chain” mechanism inactivates calcium-activated potassium channel

“Ball and chain” mechanism inactivates calcium-act...

 90

Tool for RNA tertiary structure prediction

Tool for RNA tertiary structure prediction

 168

How molecules navigate the nuclear pore complex

How molecules navigate the nuclear pore complex

 98

Nasal bacteria technique to deliver drugs bypassing the blood-brain barrier

Nasal bacteria technique to deliver drugs bypassin...

 85

Visualization of real-time protein translocation across the bacterial membrane

Visualization of real-time protein translocation a...

 77

How the brain regulates emotions

How the brain regulates emotions

 119

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

 104

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

 109

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

 135

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

 112

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

 126

Link between dietary choices and brain health

Link between dietary choices and brain health

 108

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

 131

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

 152

Males burn more fat, while females recycle it during exercise

Males burn more fat, while females recycle it duri...

 116

Paternal dietary macronutrient balance and energy intake drive metabolic and behavioral differences among offspring

Paternal dietary macronutrient balance and energy ...

 104

Research

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Beta cells intrinsically sense and limit their secretory activity via mTORC1-RhoA signaling

Beta cells intrinsically sense and limit their sec...

 0

Circulating glycerate predicts resilience to fructose- induced hepatic steatosis

Circulating glycerate predicts resilience to fruct...

 9

Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures

Divergent actions of physiological and pathologica...

 10

Antiviral discovery using sparse datasets by integrating experiments, molecular simulations, and machine learning

Antiviral discovery using sparse datasets by integ...

 14

Exploitation of rhizosphere microbiome biodiversity in plant breeding

Exploitation of rhizosphere microbiome biodiversit...

 16

Neuromelanin and selective neuronal vulnerability to Parkinson’s disease

Neuromelanin and selective neuronal vulnerability ...

 45

Cancer vaccine from intracellularly gelated tumor cells functionalized with CD47 blockage and damage-associated molecular pattern exposure

Cancer vaccine from intracellularly gelated tumor ...

 50

Serotonin and neurotensin inputs in the vCA1 dictate opposing social valence

Serotonin and neurotensin inputs in the vCA1 dicta...

 57

Bilirubin metabolism in the liver orchestrates antiviral innate immunity in the body

Bilirubin metabolism in the liver orchestrates ant...

 27

Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway

Mitochondrial DNA released by senescent tumor cell...

 93

Facial clues to conversational intentions

Facial clues to conversational intentions

 34

Intermittent fasting boosts sexual behavior by limiting the central availability of tryptophan and serotonin

Intermittent fasting boosts sexual behavior by lim...

 122

The devilish details affecting TDRL models in dopamine research

The devilish details affecting TDRL models in dopa...

 30

Beta cells intrinsically sense and limit their secretory activity via mTORC1-RhoA signaling

Beta cells intrinsically sense and limit their sec...

 0

Circulating glycerate predicts resilience to fructose- induced hepatic steatosis

Circulating glycerate predicts resilience to fruct...

 9

Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures

Divergent actions of physiological and pathologica...

 10

Antiviral discovery using sparse datasets by integrating experiments, molecular simulations, and machine learning

Antiviral discovery using sparse datasets by integ...

 14

Exploitation of rhizosphere microbiome biodiversity in plant breeding

Exploitation of rhizosphere microbiome biodiversit...

 16

Neuromelanin and selective neuronal vulnerability to Parkinson’s disease

Neuromelanin and selective neuronal vulnerability ...

 45

Cancer vaccine from intracellularly gelated tumor cells functionalized with CD47 blockage and damage-associated molecular pattern exposure

Cancer vaccine from intracellularly gelated tumor ...

 50

Serotonin and neurotensin inputs in the vCA1 dictate opposing social valence

Serotonin and neurotensin inputs in the vCA1 dicta...

 57

Bilirubin metabolism in the liver orchestrates antiviral innate immunity in the body

Bilirubin metabolism in the liver orchestrates ant...

 27

Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway

Mitochondrial DNA released by senescent tumor cell...

 93

Facial clues to conversational intentions

Facial clues to conversational intentions

 34

Intermittent fasting boosts sexual behavior by limiting the central availability of tryptophan and serotonin

Intermittent fasting boosts sexual behavior by lim...

 122

The devilish details affecting TDRL models in dopamine research

The devilish details affecting TDRL models in dopa...

 30

Minimally invasive, wide-field two-photon imaging of the brainstem at cellular resolution

Minimally invasive, wide-field two-photon imaging ...

 25

Quantitative PET imaging and modeling of molecular blood-brain barrier permeability

Quantitative PET imaging and modeling of molecular...

 33

Species-resolved profiling of antibiotic resistance genes in complex metagenomes through long-read overlapping with Argo

Species-resolved profiling of antibiotic resistanc...

 53

Integrated analysis of transcriptional and metabolic responses to mitochondrial stress

Integrated analysis of transcriptional and metabol...

 64

DNA methylation entropy is a biomarker for aging

DNA methylation entropy is a biomarker for aging

 135

Engineered nucleocytosolic vehicles for loading of programmable editors

Engineered nucleocytosolic vehicles for loading of...

 65

A cysteine-less and ultra-fast split intein rationally engineered from being aggregation-prone to highly efficient in protein trans-splicing

A cysteine-less and ultra-fast split intein ration...

 69

MetaFlowTrain: a highly parallelized and modular fluidic system for studying exometabolite-mediated inter-organismal interactions

MetaFlowTrain: a highly parallelized and modular f...

 35

Harnessing human iPSC-microglia for CNS-wide delivery of disease-modifying proteins

Harnessing human iPSC-microglia for CNS-wide deliv...

 55

Protocol for the fabrication of self-standing (nano)cellulose-based 3D scaffolds for tissue engineering

Protocol for the fabrication of self-standing (nan...

 51

Polycystins recruit cargo to distinct ciliary extracellular vesicle subtypes in C. elegans

Polycystins recruit cargo to distinct ciliary extr...

 64

MARIGOLD and MitoCIAO, two searchable compendia to visualize and functionalize protein complexes during mitochondrial remodeling

MARIGOLD and MitoCIAO, two searchable compendia to...

 99

scCamAge: A context-aware prediction engine for cellular age, aging-associated bioactivities, and morphometrics

scCamAge: A context-aware prediction engine for ce...

 70

Protein Digestion and Absorption

Protein Digestion and Absorption

 480

AlphaFold: for Protein Structure Prediction

AlphaFold: for Protein Structure Prediction

 132

Protein structure, classification, functions, properties of proteins

Protein structure, classification, functions, prop...

 223

Post Translation Modification

Post Translation Modification

 257

Protein Translation

Protein Translation

 148

Transcription, Transcription Factors, and  Chromatin Remodeling

Transcription, Transcription Factors, and Chromat...

 245

AMINO ACIDS CLASSIFICATION  AND  PROPERTIES

AMINO ACIDS CLASSIFICATION AND PROPERTIES

 303

DNA replication

DNA replication

 180

DNA Repair

DNA Repair

 212

CHROMOSOMES

CHROMOSOMES

 112

Micro RNA (miRNA)

Micro RNA (miRNA)

 115

lncRNA

lncRNA

 149

RNA Interference

RNA Interference

 89

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

 5949

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

 302

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

 303

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

 317

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

 109

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

 105

HEAD AND NECK CANCER

HEAD AND NECK CANCER

 109

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

 105

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

 109

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

 113

School Science

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Disease Science

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Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 75

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 83

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 83

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 243

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 192

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 119

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 126

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 112

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 139

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 122

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 135

APOE in Alzheimer’s

APOE in Alzheimer’s

 137

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 231

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 243

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 192

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 119

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 126

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 112

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 139

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 122

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 135

APOE in Alzheimer’s

APOE in Alzheimer’s

 137

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 231

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

 121

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

 143

Presenilin (PSEN)  in Alzheimer’s

Presenilin (PSEN)  in Alzheimer’s

 86

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 75

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 83

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 83

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