Dr. Hamid Mirzaei, PhD

Assistant Professor
Dept of Biochemistry | Center for Alzheimer's and Neurodegenerative Diseases
UT Southwestern Medical Center
Dallas, TX

Hangout Title: “Potential application of hydralazine, a FDA approved antihypertensive drug, for anti-aging therapy”
Hangout Schedule: Feb 8th: 1.30 pm CST, 2.30 pm EST, 11.30 am PST

Dr. Hamid Mirzaei  


P7C3 Neuroprotective Chemicals Function by Activating the Rate-Limiting Enzyme in NAD Salvage.
Wang G, Han T, Nijhawan D, Theodoropoulos P, Naidoo J, Yadavalli S, Mirzaei H, Pieper AA, Ready JM, McKnight SL Cell 2014 Sep 158 6 1324-34

Confetti: A Multi-protease Map of the HeLa Proteome for Comprehensive Proteomics.
Guo X, Trudgian DC, Lemoff A, Yadavalli S, Mirzaei H Mol. Cell Proteomics 2014 Apr

Systematic measurement of transcription factor-DNA interactions by targeted mass spectrometry identifies candidate gene regulatory proteins.
Mirzaei H, Knijnenburg TA, Kim B, Robinson M, Picotti P, Carter GW, Li S, Dilworth DJ, Eng JK, Aitchison JD, Shmulevich I, Galitski T, Aebersold R,
Ranish J Proc. Natl. Acad. Sci. U.S.A. 2013 Feb 110 9 3645-50

Marker for type VI secretion system effectors.
Salomon D, Kinch LN, Trudgian DC, Guo X, Klimko JA, Grishin NV, Mirzaei H, Orth K Proc. Natl. Acad. Sci. U.S.A. 2014 Jun 111 25 9271-6

GOAT - A simple LC-MS/MS gradient optimization tool.
Trudgian DC, Fischer R, Guo X, Kessler BM, Mirzaei H Proteomics 2014 Apr

Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains.
Kwon I, Kato M, Xiang S, Wu L, Theodoropoulos P, Mirzaei H, Han T, Xie S, Corden JL, McKnight SL Cell 2013 Nov 155 5 1049-60

A Gain-of-Function Mutation in DHT Synthesis in Castration-Resistant Prostate Cancer.
Chang KH, Li R, Kuri B, Lotan Y, Roehrborn CG, Liu J, Vessella R, Nelson PS, Kapur P, Guo X, Mirzaei H, Auchus RJ, Sharifi N Cell 2013 Aug 154 5 1074-84

Sulfur Amino Acids Regulate Translational Capacity and Metabolic Homeostasis through Modulation of tRNA Thiolation.
Laxman S, Sutter BM, Wu X, Kumar S, Guo X, Trudgian DC, Mirzaei H, Tu BP Cell 2013 Jul 154 2 416-29

Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Sun Q, Carrasco YP, Hu Y, Guo X, Mirzaei H, Macmillan J, Chook YM Proc. Natl. Acad. Sci. U.S.A. 2013 Jan 110 4 1303-8

Cloud CPFP: a shotgun proteomics data analysis pipeline using cloud and high performance computing.
Trudgian DC, Mirzaei H J. Proteome Res. 2012 Dec 11 12 6282-90

Honors & Awards
  • Missing Links Award - Cancer Prevention Research Institute of Texas (2011)
  • Top 10 most cited author of the year - ACS (2006)
  • Dean’s Citation for Academic Excellence - Ball State University (2001)
  • Outstanding Chemistry Graduate Student and Graduate Teaching Award - Ball State University (2001)