Rich in fat, sugar, and animal protein, the quintessential modern Western diet is often deficient in plant-derived fibers and thought to disrupt the delicate balance of human gut microbes. To explore the effects of diet on gut microbiomes, researchers sequenced DNA extracted from fecal samples from two primate species—red-shanked douc and mantled howling monkey—that were raised in zoos, sanctuaries, and nature, representing captive, semicaptive, and wild settings, respectively.
Despite being raised on vastly divergent diets in zoos as far-flung as Southeast Asia and the United States, captive primates, unlike wild-reared individuals, displayed similar gut microbiome compositions to modern humans, including a predominance of Prevotella and Bacteroidesspecies.
Sanctuary-reared primates that were fed a plant-based diet that included some of the plants available to wild-reared primates displayed middling levels of microbiome diversity and disruption, compared with zoo-reared primates of the same species.
Further, microbiome disruption was significantly associated with changes in dietary fiber content, but not with factors such as geographic location and antibiotic use, suggesting that diet largely influences microbiome composition in captive primates.
According to the authors, the findings underscore the link between fiber-rich diets and gut microbiome diversity.
http://www.pnas.org/content/early/2016/08/24/1521835113
Modern diets and gut microbiome composition
- 2,926 views
- Added
Edited
Latest News
Which of the two DNA strand…
By newseditor
Posted 16 Jun
Microglia depletion prevent…
By newseditor
Posted 16 Jun
Colorectal cancer stem cell…
By newseditor
Posted 16 Jun
Paranoia in the brain
By newseditor
Posted 16 Jun
In-vitro 3D culture of func…
By newseditor
Posted 15 Jun
Other Top Stories
Bacteria use traffic-cop-like mechanism to infect gut
Read more
A faster and cheaper way to produce new antibiotics
Read more
A device for rapid diagnosis of bacterial infections
Read more
Zika virus may cause microcephaly by hijacking human immune molecule
Read more
The mechanism of regulation of hepatitis C viral propagation and pa…
Read more
Protocols
Bioengineered human colon o…
By newseditor
Posted 14 Jun
Development of an efficient…
By newseditor
Posted 12 Jun
A co-culture system of macr…
By newseditor
Posted 10 Jun
Analysis of 3D pathology sa…
By newseditor
Posted 08 Jun
Long-term expandable mouse…
By newseditor
Posted 07 Jun
Publications
The Thermodynamics of Mind
By newseditor
Posted 17 Jun
Lost in translation: challe…
By newseditor
Posted 17 Jun
Pathways for macrophage upt…
By newseditor
Posted 16 Jun
Common and distinct neural…
By newseditor
Posted 16 Jun
Strand-resolved mutagenicit…
By newseditor
Posted 16 Jun
Presentations
Myelin plasticity in the ve…
By newseditor
Posted 10 Jun
Hydrogels in Drug Delivery
By newseditor
Posted 12 Apr
Lipids
By newseditor
Posted 31 Dec
Cell biology of carbohydrat…
By newseditor
Posted 29 Nov
RNA interference (RNAi)
By newseditor
Posted 23 Oct
Posters
A chemical biology/modular…
By newseditor
Posted 22 Aug
Single-molecule covalent ma…
By newseditor
Posted 04 Jul
ASCO-2020-HEALTH SERVICES R…
By newseditor
Posted 23 Mar
ASCO-2020-HEAD AND NECK CANCER
By newseditor
Posted 23 Mar
ASCO-2020-GENITOURINARY CAN…
By newseditor
Posted 23 Mar