Blood samples from infants who died of Sudden Infant Death Syndrome (SIDS) had high levels of serotonin, a chemical that carries signals along and between nerves, according to a study. The finding raises the possibility that a test could be developed to distinguish SIDS cases from other causes of sleep-related, unexpected infant death. The study appears in the Proceedings of the National Academy of Sciences.
SIDS is the sudden death of an infant under one year of age that remains unexplained after a complete autopsy and death scene investigation. In the current study, researchers reported that 31 percent of SIDS infants (19 of 61) had elevated blood levels of serotonin. In previous studies, the researchers reported multiple serotonin-related brain abnormalities in SIDS cases, including a decrease in serotonin in regions involved in breathing, heart rate patterns, blood pressure, temperature regulation, and arousal during sleep.
Taken together, the researchers wrote, the findings suggest that an abnormality in serotonin metabolism could indicate an underlying vulnerability that increases SIDS risk and that testing blood samples for serotonin could distinguish certain SIDS cases from other infant deaths. However, they caution that more research is needed.
https://www.nichd.nih.gov/news/releases/Pages/070517-SIDS-serotonin.aspx
http://www.pnas.org/content/early/2017/06/29/1617374114.full
Blood of SIDS (Sudden Infant Death Syndrome) infants contains high levels of serotonin
- 8,082 views
- Added
Edited
Latest News
Father's gut microbes affec…
By newseditor
Posted 08 May
A new brain circuit in mice…
By newseditor
Posted 08 May
Mechanism of choline entry…
By newseditor
Posted 07 May
Link between UTI and breast…
By newseditor
Posted 07 May
Sleep resets brain connections
By newseditor
Posted 07 May
Other Top Stories
Peripheral immune system and microglia implicated in multiple scler…
Read more
A new mechanism for the transfer of maternal mitochondrial DNA
Read more
PTSD has a strong genetic component like other psychiatric disorders
Read more
Chromosomal errors behind women's biological clock
Read more
Social status affects gene regulation in monkeys
Read more
Protocols
Single-cell adhesive profil…
By newseditor
Posted 07 May
Parasympathetic neurons der…
By newseditor
Posted 07 May
Non-invasive measurements o…
By newseditor
Posted 05 May
A validation strategy to as…
By newseditor
Posted 04 May
Generation of rat forebrain…
By newseditor
Posted 03 May
Publications
Paternal microbiome perturb…
By newseditor
Posted 08 May
Truncating NFKB1 variants c…
By newseditor
Posted 08 May
Synaptotagmin-11 facilitate…
By newseditor
Posted 08 May
Astrocytic Slc4a4 regulates…
By newseditor
Posted 08 May
Diabetic retinopathy is a c…
By newseditor
Posted 08 May
Presentations
Hydrogels in Drug Delivery
By newseditor
Posted 12 Apr
Lipids
By newseditor
Posted 31 Dec
Cell biology of carbohydrat…
By newseditor
Posted 29 Nov
RNA interference (RNAi)
By newseditor
Posted 23 Oct
RNA structure and functions
By newseditor
Posted 19 Oct
Posters
A chemical biology/modular…
By newseditor
Posted 22 Aug
Single-molecule covalent ma…
By newseditor
Posted 04 Jul
ASCO-2020-HEALTH SERVICES R…
By newseditor
Posted 23 Mar
ASCO-2020-HEAD AND NECK CANCER
By newseditor
Posted 23 Mar
ASCO-2020-GENITOURINARY CAN…
By newseditor
Posted 23 Mar