Maternal diet and tissue-resident macrophages

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Maternal diet and tissue-resident macrophages

Maternal diet durably programs tissue resident macrophages across fetal and early postnatal development. 

Developmental programming by maternal overnutrition perturbs tissue-resident macrophage functions.

Developmentally mistuned macrophages render offspring susceptible to various noncommunicable diseases, serving as intergenerational messengers.

https://www.cell.com/trends/immunology/fulltext/S1471-4906(25)00301-1

https://sciencemission.com/Maternal-diet-shapes-TRMs