Index - Sciencemission

Science Hangouts

Daily Well-Being

Science Hangouts

Daily Well-Being

330

A twist of fate: age-related declines in the longevity protein, Klotho, drive impaired skeletal muscle regeneration

Science Hangouts

A twist of fate: age-related declines in the longevity protein, Klotho, drive impaired skeletal muscle regeneration

1070

Understanding Cancer: From Development to Therapy

Science Hangouts

Understanding Cancer: From Development to Therapy

321

Atomic Force Microscopy: Towards Medical Applications.

Science Hangouts

Atomic Force Microscopy: Towards Medical Applications.

59

A Novel Atypical Sperm Centriole is Functional During Fertilization

Science Hangouts

A Novel Atypical Sperm Centriole is Functional During Fertilization

64

GABAergic signaling at the Axon Initial Segment

Science Hangouts

GABAergic signaling at the Axon Initial Segment

63

Science News Highlights

Mechanism of multiple functions of HMGB1

News highlights

Mechanism of multiple functions of HMGB1

12

ALS-causing SOD1 mutants form distinct amyloid fibril structures

News highlights

ALS-causing SOD1 mutants form distinct amyloid fibril ...

9

GCN2 acts as a glutamine sensor for mTORC1

News highlights

GCN2 acts as a glutamine sensor for mTORC1

12

News

Dual nature of polyamines in longevity to cancer

Dual nature of polyamines in longevity to cancer

3

Surprising role of Cas9 as a guardian of bacterial defense

Surprising role of Cas9 as a guardian of bacterial...

3

Epigenomic rewiring in Alzheimer’s disease progression and cognitive resilience

Epigenomic rewiring in Alzheimer’s disease progres...

5

Diabetes changes the shape of our hearts

Diabetes changes the shape of our hearts

17

Ultrasound enables deep brain stimulation in people without surgery

Ultrasound enables deep brain stimulation in peopl...

11

Tumors hijack macrophages for iron supply to promote bone metastasis and anemia

Tumors hijack macrophages for iron supply to promo...

31

Gene defect slows brain’s cleanup, driving Alzheimer’s risk

Gene defect slows brain’s cleanup, driving Alzheim...

29

AI reveals how protein modifications link mutations to disease

AI reveals how protein modifications link mutation...

30

ADAR1 loss impairs glioblastoma tumor growth

ADAR1 loss impairs glioblastoma tumor growth

41

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

24

Link between excessive alcohol and fatty liver disease

Link between excessive alcohol and fatty liver dis...

53

Viral mechanism behind nasopharyngeal cancer spread

Viral mechanism behind nasopharyngeal cancer spread

45

How capillary constriction triggers metastasis

How capillary constriction triggers metastasis

48

Epigenomic rewiring in Alzheimer’s disease progression and cognitive resilience

Epigenomic rewiring in Alzheimer’s disease progres...

5

Gene defect slows brain’s cleanup, driving Alzheimer’s risk

Gene defect slows brain’s cleanup, driving Alzheim...

29

Vasopressin, a neuropeptide, regulates both sociability and social aggression

Vasopressin, a neuropeptide, regulates both sociab...

47

Brain’s immune cells key to wiring the adolescent brain

Brain’s immune cells key to wiring the adolescent ...

30

Rewiring addiction with designer proteins

Rewiring addiction with designer proteins

33

Microglial STING protects against neurological decline with age

Microglial STING protects against neurological dec...

86

The gut immune system is altered in mouse model of Alzheimer’s

The gut immune system is altered in mouse model of...

14

Traumatic brain injury treatment with selenized neural stem cell-derived exosomes

Traumatic brain injury treatment with selenized ne...

56

Brain stem pain circuit

Brain stem pain circuit

45

Brain’s map of the body remains unchanged after amputation

Brain’s map of the body remains unchanged after am...

42

A new analgesic promises pain relief with fewer downsides

A new analgesic promises pain relief with fewer do...

46

Brain area 46 is at the center of a network for emotion regulation in marmosets

Brain area 46 is at the center of a network for em...

101

Gut–immune–brain axis modulation of autism using precision-selected probiotics

Gut–immune–brain axis modulation of autism using p...

82

Tumors hijack macrophages for iron supply to promote bone metastasis and anemia

Tumors hijack macrophages for iron supply to promo...

31

ADAR1 loss impairs glioblastoma tumor growth

ADAR1 loss impairs glioblastoma tumor growth

41

How capillary constriction triggers metastasis

How capillary constriction triggers metastasis

48

Biomolecular condensates implicated in a childhood brain cancer

Biomolecular condensates implicated in a childhood...

29

A key gene complex promotes blood cancer growth

A key gene complex promotes blood cancer growth

45

Breast tumors tunnel into fat cells to fuel up

Breast tumors tunnel into fat cells to fuel up

52

Cancer-associated nerve injury leads to chronic inflammation and immunotherapy resistance

Cancer-associated nerve injury leads to chronic in...

90

Targeting vagal brain-liver axis to combat cancer-associated cachexia

Targeting vagal brain-liver axis to combat cancer-...

241

How glucose fuels cancer-fighting immune cells

How glucose fuels cancer-fighting immune cells

254

Detecting early-stage tumors with a blood sample

Detecting early-stage tumors with a blood sample

211

Targeting liver tumor metabolism rewires immune function and suppress cancer progression

Targeting liver tumor metabolism rewires immune fu...

229

Key genes controlling brain tumor spread identified

Key genes controlling brain tumor spread identified

251

Gene signature an early warning system for aggressive pancreatic cancer

Gene signature an early warning system for aggress...

223

Neuritin 1 acts as a local metabolic regulator of brown adipose tissue

Neuritin 1 acts as a local metabolic regulator of ...

33

How cilia regulate development of precursor cells in fat tissue

How cilia regulate development of precursor cells ...

79

How weight loss drugs target the brain and pancreas

How weight loss drugs target the brain and pancreas

119

Glucose transporter dysregulation in type 2-diabetes

Glucose transporter dysregulation in type 2-diabetes

165

Epigenetic biomarkers predict cardiovascular risk for type 2 diabetes patients

Epigenetic biomarkers predict cardiovascular risk ...

220

Microproteins regulating adipocyte proliferation and lipid metabolism

Microproteins regulating adipocyte proliferation a...

187

Beta cell transcription-splicing axis is disrupted in type 2 diabetes

Beta cell transcription-splicing axis is disrupted...

208

Fat in muscle prevents muscle regeneration

Fat in muscle prevents muscle regeneration

240

Misfolded proteins accumulate in the mitochondria of patients with type 2 diabetes

Misfolded proteins accumulate in the mitochondria ...

249

Body temperature regulates glucose metabolism

Body temperature regulates glucose metabolism

211

Weight loss alters adipose tissue beyond just reducing fat

Weight loss alters adipose tissue beyond just redu...

567

Reduction in amino acid cysteine triggers weight loss

Reduction in amino acid cysteine triggers weight loss

291

GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity

GRK-biased adrenergic agonists for the treatment o...

254

AI reveals how protein modifications link mutations to disease

AI reveals how protein modifications link mutation...

30

An open-source AI platform to democratize protein design

An open-source AI platform to democratize protein ...

70

Proteomics and AI detects early signs of ALS in plasma years before symptoms appear

Proteomics and AI detects early signs of ALS in pl...

60

Generative AI platform for mRNA therapeutics

Generative AI platform for mRNA therapeutics

50

Generative AI to design novel antibiotics

Generative AI to design novel antibiotics

40

How the brain constructs emotional experiences

How the brain constructs emotional experiences

188

AI to predict markers of Alzheimer’s disease

AI to predict markers of Alzheimer’s disease

235

Circulating epigenetic signatures classifying brain insulin resistance in humans

Circulating epigenetic signatures classifying brai...

204

How an artificial protein emerges from fitting together individual components

How an artificial protein emerges from fitting tog...

214

AI-powered notch ligand design to enhance T-cell based immunotherapies

AI-powered notch ligand design to enhance T-cell b...

211

Generative AI learns to read medical images with far less data

Generative AI learns to read medical images with f...

176

How AI can enhance early detection of emerging viruses

How AI can enhance early detection of emerging vir...

206

AI Agents in Virtual Lab Design New SARS-CoV-2 Nanobodies

AI Agents in Virtual Lab Design New SARS-CoV-2 Nan...

192

RNA nanoparticle gene therapy to prevent premature skull fusion in newborns

RNA nanoparticle gene therapy to prevent premature...

27

Cubosome-based method for loading mRNA into exosomes

Cubosome-based method for loading mRNA into exosomes

219

Challenges to lipid nanoparticle mediated delivery of RNA to the cytosol

Challenges to lipid nanoparticle mediated delivery...

202

Programmable gene insertion in human cells using a new gene editor

Programmable gene insertion in human cells using a...

289

New lipid nanoparticle platform delivers mRNA to the brain through the blood-brain barrier

New lipid nanoparticle platform delivers mRNA to t...

435

Microfluidic protocol to extract and purify DNA

Microfluidic protocol to extract and purify DNA

301

Artificial sensing system using synthetic neurons

Artificial sensing system using synthetic neurons

395

The nanoparticle-based vaccine against many variants of SARS-CoV-2

The nanoparticle-based vaccine against many varian...

337

Nanoparticle-based itaconate treatment for atherosclerotic plaque resolution

Nanoparticle-based itaconate treatment for atheros...

356

A lipid nanoparticle delivers mRNA cure for pre-eclampsia

A lipid nanoparticle delivers mRNA cure for pre-ec...

349

‘Supercharging’ T cells with mitochondria enhances their antitumor activity

‘Supercharging’ T cells with mitochondria enhances...

327

Can we ‘recharge’ our cells?

Can we ‘recharge’ our cells?

358

Ureteral organoid from pluripotent stem cells

Ureteral organoid from pluripotent stem cells

25

Progenitor neighborhood signaling in neurogenesis

Progenitor neighborhood signaling in neurogenesis

35

Evolutionary changes in the developing human intestine

Evolutionary changes in the developing human intes...

209

Human kidney organoids from stem cells

Human kidney organoids from stem cells

191

Human bone marrow stem cell metabolism altered by aging and cancer

Human bone marrow stem cell metabolism altered by ...

238

Serine deprivation switches hair follicle stem cells into skin healers during injury

Serine deprivation switches hair follicle stem cel...

213

Producing library of heterogeneous human neurons from stem cells

Producing library of heterogeneous human neurons f...

266

Bile acid supplementation gives rise to grape-like liver organoid clusters

Bile acid supplementation gives rise to grape-like...

220

Proliferating neural progenitors identified in the adult human hippocampus

Proliferating neural progenitors identified in the...

202

Senescence-resistant human mesenchymal progenitor cells counter aging

Senescence-resistant human mesenchymal progenitor ...

258

Glial replacement therapy slows Huntington’s disease

Glial replacement therapy slows Huntington’s disease

243

A rapid method for building vascular organoids

A rapid method for building vascular organoids

238

Platform for in vitro production of human microglia cells from iPSC

Platform for in vitro production of human microgli...

256

AI and lab tests to predict genetic disease risk

AI and lab tests to predict genetic disease risk

52

Genetic test predicts obesity in childhood

Genetic test predicts obesity in childhood

181

Analysis of India's genetic diversity

Analysis of India's genetic diversity

211

ITSN1 gene linked to substantial risk of Parkinson’s disease

ITSN1 gene linked to substantial risk of Parkinson...

322

Disordered renal metabolism in myotonic dystrophy type 1

Disordered renal metabolism in myotonic dystrophy ...

299

Gene ‘silencer’ in junk DNA prevents fatal neurological disease

Gene ‘silencer’ in junk DNA prevents fatal neurolo...

282

The role of moms X chromosome in cognition and aging of daughter

The role of moms X chromosome in cognition and agi...

294

Genes for depression across ethnicities

Genes for depression across ethnicities

313

Gene editing extends lifespan in mouse model of prion disease

Gene editing extends lifespan in mouse model of pr...

270

Two new gene variants linked to epilepsy identified!

Two new gene variants linked to epilepsy identified!

293

Dysregulation of mTOR signalling is a converging mechanism in lissencephaly

Dysregulation of mTOR signalling is a converging m...

347

The role of rare germline structural variants in pediatric solid tumors

The role of rare germline structural variants in p...

295

Linking genetic risk for schizophrenia to a malformed skull

Linking genetic risk for schizophrenia to a malfor...

281

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

24

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

308

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

336

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

311

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

313

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

196

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

293

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

303

Role of ECM in brain memory

Role of ECM in brain memory

297

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

305

Supramolecular anticoagulants with on-demand reversibility

Supramolecular anticoagulants with on-demand rever...

301

Cell vulnerability 'fingerprint' related to Parkinson's identified!

Cell vulnerability 'fingerprint' related to Parkin...

299

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

180

Diabetes changes the shape of our hearts

Diabetes changes the shape of our hearts

17

High-salt diet inflames the brain and raises blood pressure

High-salt diet inflames the brain and raises blood...

107

Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA

Platelets sequester extracellular DNA, capturing t...

197

Role of a protein tyrosine phosphatase 1B (PTP1B) in heart disease

Role of a protein tyrosine phosphatase 1B (PTP1B) ...

261

Gut bacteria derived molecule promotes atherosclerosis

Gut bacteria derived molecule promotes atheroscler...

500

Key mechanism of brain repair in vascular dementia

Key mechanism of brain repair in vascular dementia

204

Fixing cholesterol metabolism problem to prevent blindness

Fixing cholesterol metabolism problem to prevent b...

233

Similarities between atherosclerotic blood vessels and tumor development

Similarities between atherosclerotic blood vessels...

251

TMEM65 regulates mitochondrial calcium efflux

TMEM65 regulates mitochondrial calcium efflux

270

Inhibition of ceramide synthesis contributes to cardiometabolic diseases

Inhibition of ceramide synthesis contributes to ca...

255

How a Y chromosome gene may shape the course of heart valve disease

How a Y chromosome gene may shape the course of he...

372

Why babies recover, but adults scar, after heart damage

Why babies recover, but adults scar, after heart d...

272

Testosterone increases damage following a heart attack

Testosterone increases damage following a heart at...

267

A keto diet might benefit females more than males

A keto diet might benefit females more than males

65

Ultra-processed food consumption decreased sperm motility

Ultra-processed food consumption decreased sperm m...

101

Estrogen inhibit ferroptosis and acute kidney injury

Estrogen inhibit ferroptosis and acute kidney injury

168

Sex differences in tissue-specific immunity and immunology

Sex differences in tissue-specific immunity and im...

231

New gene therapy for X-linked Rett syndrome in girls

New gene therapy for X-linked Rett syndrome in girls

208

Cryo-EM structures reveal how GnRH activates its receptor

Cryo-EM structures reveal how GnRH activates its r...

199

High blood pressure in pregnancy linked to increased risk of seizure in children

High blood pressure in pregnancy linked to increas...

220

Iron in sex determination of mammalian embryos

Iron in sex determination of mammalian embryos

234

Temperature-controlled calcium channel, CatSper activates sperm

Temperature-controlled calcium channel, CatSper ac...

271

How mothers adapt to the metabolic demands of nursing

How mothers adapt to the metabolic demands of nursing

268

A protein complex critical to male fertility uncovered!

A protein complex critical to male fertility uncov...

285

Association between placental DNA methylation and schizophrenia

Association between placental DNA methylation and ...

661

Interactions between sex hormones and neurological health

Interactions between sex hormones and neurological...

370

Dual nature of polyamines in longevity to cancer

Dual nature of polyamines in longevity to cancer

3

Surprising role of Cas9 as a guardian of bacterial defense

Surprising role of Cas9 as a guardian of bacterial...

3

Link between excessive alcohol and fatty liver disease

Link between excessive alcohol and fatty liver dis...

53

Cells measure RNA tails with a molecular stopwatch

Cells measure RNA tails with a molecular stopwatch

46

Newly discovered purging process in gastric cells

Newly discovered purging process in gastric cells

41

How calcium is transported at a superfast speed by Ca2+-ATPases

How calcium is transported at a superfast speed by...

51

How lysosome deals with stress

How lysosome deals with stress

143

Promotor demethylation reverses β-hemoglobinopathies

Promotor demethylation reverses β-hemoglobinopathies

174

Unknown “folding factories” for proteins identified!

Unknown “folding factories” for proteins identified!

233

Molecular drivers of cellular differentiation

Molecular drivers of cellular differentiation

221

Preventing premature protein release

Preventing premature protein release

216

How mitochondrial stress softens the cell nucleus and alters cellular identity

How mitochondrial stress softens the cell nucleus ...

442

Vitamin B1 stops deadly lactate production to reduce sepsis lethality

Vitamin B1 stops deadly lactate production to redu...

300

Viral mechanism behind nasopharyngeal cancer spread

Viral mechanism behind nasopharyngeal cancer spread

45

Three potent human antibodies against mpox

Three potent human antibodies against mpox

38

Human metabolic pathways that Cryptosporidium, an intestinal parasite, requires to survive

Human metabolic pathways that Cryptosporidium, an ...

179

Antifungal drug candidate identified!

Antifungal drug candidate identified!

173

Multi-antigen vaccine strategy for Betacoronaviruses

Multi-antigen vaccine strategy for Betacoronaviruses

162

Sugar coatings of RNA help in immune evasion

Sugar coatings of RNA help in immune evasion

205

How leukemia virus stays hidden in the body

How leukemia virus stays hidden in the body

196

Respiratory viruses can wake up breast cancer cells in lungs

Respiratory viruses can wake up breast cancer cell...

187

Quantifying molecules produced by gut microbiota and their influence to our body

Quantifying molecules produced by gut microbiota a...

329

How phages defeat antibiotic resistant bacteria

How phages defeat antibiotic resistant bacteria

259

How ticks defend themselves against a deadly virus

How ticks defend themselves against a deadly virus

31

Albumin redirects metabolism to turn harmless Candida albicans into dangerous pathogens

Albumin redirects metabolism to turn harmless Cand...

203

The Covid-19 pandemic may have aged our brains

The Covid-19 pandemic may have aged our brains

275

Controlling cilia formation in mammalian embryos

Controlling cilia formation in mammalian embryos

33

Neurodevelopmental disorders from loss of Polβ in developing neurons

Neurodevelopmental disorders from loss of Polβ in ...

108

Epigenetic regulation of neural stem cell aging

Epigenetic regulation of neural stem cell aging

185

A molecular mechanism affecting ciliopathies uncovered!

A molecular mechanism affecting ciliopathies uncov...

220

Novel mechanism for regulating ribosome biogenesis during brain development

Novel mechanism for regulating ribosome biogenesis...

222

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

204

New stem cell model sheds light on human amniotic sac development

New stem cell model sheds light on human amniotic ...

230

MicroRNAs guide the development of Purkinje cells

MicroRNAs guide the development of Purkinje cells

348

Ancient viral DNA shapes early embryo development

Ancient viral DNA shapes early embryo development

277

Mechanism to bring newborn neurons out of the neuronal nest

Mechanism to bring newborn neurons out of the neur...

318

Leptin in neurodevelopment!

Leptin in neurodevelopment!

306

Role of Integrator in early neural fate commitment

Role of Integrator in early neural fate commitment

307

Impaired chaperonin function may cause brain malformations and seizures

Impaired chaperonin function may cause brain malfo...

324

Potato evolved from tomato 9 million years ago

Potato evolved from tomato 9 million years ago

279

How plants sense heat during the day

How plants sense heat during the day

259

Mechanism of auxin influx in plants

Mechanism of auxin influx in plants

215

Plant-based protein is linked to a longer life

Plant-based protein is linked to a longer life

270

Epigenetic marker is essential for Marchantia sperm function

Epigenetic marker is essential for Marchantia sper...

269

Anti-bacterial role of plant metabolite

Anti-bacterial role of plant metabolite

290

Key genes to fight against crop parasites identified!

Key genes to fight against crop parasites identified!

264

CoQ10-producing rice with gene editing

CoQ10-producing rice with gene editing

274

Bacteria used to amplify plant hormones

Bacteria used to amplify plant hormones

272

Protein protects biological nitrogen fixation from oxidative stress

Protein protects biological nitrogen fixation from...

314

Plant roots change their growth pattern during ‘puberty’

Plant roots change their growth pattern during ‘pu...

308

The biosynthesis of steroidal defense metabolites in plants

The biosynthesis of steroidal defense metabolites ...

317

Decoding plant-to-fungi communication

Decoding plant-to-fungi communication

318

Cellular “toolkit” to reprogram immune cells for cancer therapy

Cellular “toolkit” to reprogram immune cells for c...

83

New monoclonal antibody targets deadly sepsis

New monoclonal antibody targets deadly sepsis

47

How cells in small intestine of people with coeliac disease communicate with one another

How cells in small intestine of people with coelia...

123

Gut neurons help the body fight inflammation

Gut neurons help the body fight inflammation

146

Breast milk maternal antibodies regulate early neonatal immune responses in mouse gut

Breast milk maternal antibodies regulate early neo...

174

Cysteinyl leukotrienes stimulate gut absorption of food allergens to promote anaphylaxis

Cysteinyl leukotrienes stimulate gut absorption of...

161

How the immune system fends off gut parasites

How the immune system fends off gut parasites

263

How pH impacts the immune system

How pH impacts the immune system

365

A deubiquitinase prevents ulcerative colitis by inhibiting microbiota-mediated STING activation

A deubiquitinase prevents ulcerative colitis by in...

218

How modified RNA tricks the innate immune system

How modified RNA tricks the innate immune system

296

New protein target to control chronic inflammation

New protein target to control chronic inflammation

211

Mechanism to suppress T cell activation and autoimmunity

Mechanism to suppress T cell activation and autoim...

262

How neuroendocrine cells protect lung airways?

How neuroendocrine cells protect lung airways?

203

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

280

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

177

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

622

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

255

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

244

Printed skin to replace animal testing

Printed skin to replace animal testing

270

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

243

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

249

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

268

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

283

Ultrasound enables deep brain stimulation in people without surgery

Ultrasound enables deep brain stimulation in peopl...

11

The first structure of the complete botulinum neurotoxin complex

The first structure of the complete botulinum neur...

40

Fat microscopy to image lipids in cells

Fat microscopy to image lipids in cells

148

Brain-computer interface could decode inner speech in real time

Brain-computer interface could decode inner speech...

45

PathoPlex maps the location of proteins inside cells

PathoPlex maps the location of proteins inside cells

119

Cells change shape to deal with wounds

Cells change shape to deal with wounds

112

New computer method enables comprehensive identification of omega fatty acids

New computer method enables comprehensive identifi...

184

Turning bacteria into tiny pollution detectors

Turning bacteria into tiny pollution detectors

176

Blood proteome regulation to control inflammation, age-associated organ dysfunction and mortality in sepsis

Blood proteome regulation to control inflammation,...

231

High-speed mapping of whole-mouse peripheral nerves

High-speed mapping of whole-mouse peripheral nerves

218

Platform for annotating and interpreting single-cell populations

Platform for annotating and interpreting single-ce...

215

‘Superfamily’ of bacterial predator proteins uncovered!

‘Superfamily’ of bacterial predator proteins uncov...

238

A single brain scan can tell how fast you're aging

A single brain scan can tell how fast you're aging

210

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

220

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

204

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

219

How the brain regulates emotions

How the brain regulates emotions

302

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

289

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

285

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

322

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

298

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

311

Link between dietary choices and brain health

Link between dietary choices and brain health

289

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

193

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

341

Males burn more fat, while females recycle it during exercise

Males burn more fat, while females recycle it duri...

300

Research

Polyamines stimulate the protein synthesis of the translation initiation factor eIF5A2, participating in mRNA decoding, distinct from eIF5A1

Polyamines stimulate the protein synthesis of the ...

5

Cas9 senses CRISPR RNA abundance to regulate CRISPR spacer acquisition

Cas9 senses CRISPR RNA abundance to regulate CRISP...

5

Single-cell multiregion epigenomic rewiring in Alzheimer’s disease progression and cognitive resilience

Single-cell multiregion epigenomic rewiring in Alz...

6

Left ventricular myocardial molecular profile of h...

13

Ultrasound system for precise neuromodulation of human deep brain circuits

Ultrasound system for precise neuromodulation of h...

6

Intrinsic disorder and fuzzy interactions drive multiple functions of HMGB1

Intrinsic disorder and fuzzy interactions drive mu...

21

Distinct amyloid fibril structures formed by ALS-causing SOD1 mutants G93A and D101N

Distinct amyloid fibril structures formed by ALS-c...

24

mTORC1 senses glutamine and other amino acids through GCN2

mTORC1 senses glutamine and other amino acids thro...

29

DeepMVP: deep learning models trained on high-quality data accurately predict PTM sites and variant-induced alterations

DeepMVP: deep learning models trained on high-qual...

22

Cancer cell and microenvironmental rewiring by ADAR1 loss impairs glioblastoma tumor growth and extends survival

Cancer cell and microenvironmental rewiring by ADA...

23

The mechanotransducer Piezo1 coordinates metabolism and inflammation to promote skin growth

The mechanotransducer Piezo1 coordinates metabolis...

26

Maternal gut microbiome during early pregnancy predicts preterm birth

Maternal gut microbiome during early pregnancy pre...

27

The interplay between organized lymphoid structures and thermogenic adipose tissue

The interplay between organized lymphoid structure...

41

Polyamines stimulate the protein synthesis of the translation initiation factor eIF5A2, participating in mRNA decoding, distinct from eIF5A1

Polyamines stimulate the protein synthesis of the ...

5

Cas9 senses CRISPR RNA abundance to regulate CRISPR spacer acquisition

Cas9 senses CRISPR RNA abundance to regulate CRISP...

5

Single-cell multiregion epigenomic rewiring in Alzheimer’s disease progression and cognitive resilience

Single-cell multiregion epigenomic rewiring in Alz...

6

Left ventricular myocardial molecular profile of h...

13

Ultrasound system for precise neuromodulation of human deep brain circuits

Ultrasound system for precise neuromodulation of h...

6

Intrinsic disorder and fuzzy interactions drive multiple functions of HMGB1

Intrinsic disorder and fuzzy interactions drive mu...

21

Distinct amyloid fibril structures formed by ALS-causing SOD1 mutants G93A and D101N

Distinct amyloid fibril structures formed by ALS-c...

24

mTORC1 senses glutamine and other amino acids through GCN2

mTORC1 senses glutamine and other amino acids thro...

29

Cancer cell and microenvironmental rewiring by ADAR1 loss impairs glioblastoma tumor growth and extends survival

Cancer cell and microenvironmental rewiring by ADA...

23

The mechanotransducer Piezo1 coordinates metabolism and inflammation to promote skin growth

The mechanotransducer Piezo1 coordinates metabolis...

26

Maternal gut microbiome during early pregnancy predicts preterm birth

Maternal gut microbiome during early pregnancy pre...

27

The interplay between organized lymphoid structures and thermogenic adipose tissue

The interplay between organized lymphoid structure...

41

Virus-human chromatin interactions reorganise 3D genome and hijack KDM5B for promoting metastasis in nasopharyngeal carcinoma

Virus-human chromatin interactions reorganise 3D g...

20

DeepMVP: deep learning models trained on high-quality data accurately predict PTM sites and variant-induced alterations

DeepMVP: deep learning models trained on high-qual...

22

Engineering infrared light detection in blind human retina using ultrasensitive human TRPV1 channels

Engineering infrared light detection in blind huma...

63

One-shot design of functional protein binders with BindCraft

One-shot design of functional protein binders with...

70

Engineering chimeric signaling proteins for microbial whole-cell biosensors: from design to deployment

Engineering chimeric signaling proteins for microb...

80

Quantitative imaging of lipid transport in mammalian cells

Quantitative imaging of lipid transport in mammali...

95

Mucus-inspired hydrogels with protonation-driven adhesion for extreme acidic conditions

Mucus-inspired hydrogels with protonation-driven a...

43

Highly efficient prime editors for mammalian genome editing based on porcine retrovirus reverse transcriptase

Highly efficient prime editors for mammalian genom...

64

Wearable face mask-attached disposable printed sensor arrays for point-of-need monitoring of alkaline gases in breath

Wearable face mask-attached disposable printed sen...

76

Single-cell omics sequencing technologies: the long-read generation

Single-cell omics sequencing technologies: the lon...

59

Rapid generation of functional vascular organoids via simultaneous transcription factor activation of endothelial and mural lineages

Rapid generation of functional vascular organoids ...

384

Computationally unmasking each fatty acyl C=C position in complex lipids by routine LC-MS/MS lipidomics

Computationally unmasking each fatty acyl C=C posi...

380

Fusogenic lipid nanoparticles for rapid delivery of large therapeutic molecules to exosomes

Fusogenic lipid nanoparticles for rapid delivery o...

400

Rational engineering of allosteric protein switches by in silico prediction of domain insertion sites

Rational engineering of allosteric protein switche...

390

PARKINSON’S DISEASE

PARKINSON’S DISEASE

937

Anatomy of the Cerebellum

Anatomy of the Cerebellum

997

Anatomy of the Hippocampus

Anatomy of the Hippocampus

1044

Cerebral Cortex

Cerebral Cortex

1034

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

332

Protein Digestion and Absorption

Protein Digestion and Absorption

697

AlphaFold: for Protein Structure Prediction

AlphaFold: for Protein Structure Prediction

304

Protein structure, classification, functions, properties of proteins

Protein structure, classification, functions, prop...

453

Post Translation Modification

Post Translation Modification

438

Protein Translation

Protein Translation

336

Transcription, Transcription Factors, and Chromatin Remodeling

Transcription, Transcription Factors, and Chromat...

429

AMINO ACIDS CLASSIFICATION AND PROPERTIES

AMINO ACIDS CLASSIFICATION AND PROPERTIES

516

DNA replication

DNA replication

386

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

25274

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

886

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

829

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

1254

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

297

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

291

HEAD AND NECK CANCER

HEAD AND NECK CANCER

309

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

156

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

286

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

312

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

249

Gestational diabetes therapeutics

Gestational diabetes therapeutics

250

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

271

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

435

Different types of Alzheimer's disease

Different types of Alzheimer's disease

346

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

299

Alzheimer’s therapeutics

Alzheimer’s therapeutics

301

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

281

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

320

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

266

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

294

APOE in Alzheimer’s

APOE in Alzheimer’s

294

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

419

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

435

Different types of Alzheimer's disease

Different types of Alzheimer's disease

346

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

299

Alzheimer’s therapeutics

Alzheimer’s therapeutics

301

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

281

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

320

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

266

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

294

APOE in Alzheimer’s

APOE in Alzheimer’s

294

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

419

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

288

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

320

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

253

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

249

Gestational diabetes therapeutics

Gestational diabetes therapeutics

250

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

271