Modulating inflammatory rhythms in rheumatoid arthritis via dietary timimg
Mechanisms governing the inflammatory rhythms in rheumatoid arthritis in not well understood.
The researchers demonstrate that dietary timing modulates rheumatoid arthritis inflammatory rhythms by inducing diurnal oscillations in gut microbiota.
Particularly, Parabacteroides distasonis utilizes b-glucosidase to release glycitein, which mitigates RA inflammation via the SIRT5-NF-kB axis.
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(24)00334-6
