Opsin 5 mediates mammalian cornea wound healing
Being at the ocular surface, transparent cornea is uniquely in danger of injury.
The researchers demonstrate that mechanical injury to the surface of the cornea induces temporary expression of an opsin photoreceptor, Opn5, in mice and primates. Corneas lacking Opn5 have markedly impaired wound healing.
The induction of this photoreceptor is associated with accelerated healing in the presence of violet light.
https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00816-2
