The neurobiology of overeating
Obesity is a pandemic currently, arises from overeating of food resulting in serious health challenges.
Intricate relationship between overeating, obesity, and the underlying neurobiological mechanisms is discussed in this overview. We review
They also evaluate the role of the hypothalamus and reward systems in controlling food intake and energy balance and the dysregulation in both these systems leads to overeating, as seen in genetic syndromes and environmental models.
The also examine the concept of ‘‘food addiction’’ and discuss addiction-related behavior and current treatments—in particular, GLP-1 receptor agonists.
Unraveling the neurobiological basis of overeating and developing effective interventions for maladaptive feeding behaviors may help to address overeating behavior and obesity mediated health challenges.
