Type 2 immunity in cancer
In addition to its role in defence against parasitic helminth infections, type 2 immunity through various mechanisms, including the suppression of excessive type 1 immune responses, regulation of tissue repair and maintenance of adipose tissue homeostasis, safeguards the host.
Type 2 immunity has been perceived as a potential promoter of tumorigenesis but the recent studies challenges this notion.
In this Review, the researchers discuss the role of type 2 immunity in reshaping the landscape of cancer immunotherapies.
