Identification and characterization of a nonbiological small-molecular mimic of a Zika virus conformational neutralizing epitope
Antigenic similarities between Zika virus (ZIKV) and other flaviviruses pose challenges to the development of virus-specific diagnostic tools and effective vaccines. Starting with a DNA-encoded one-bead-one-compound combinatorial library of 508,032 syn- thetic, non-natural oligomers, we selected and characterized small molecules that mimic ZIKV epitopes.Read more
