Auxin–calcium signaling crosstalk in plants
Both auxin and calcium act as versatile regulators of plant growth and development.
Non-transcriptional auxin signaling regulates root growth within seconds through Ca2+ dynamics.
Auxin Signaling F-Box 1 (AFB1)–cyclic nucleotide-gated channel 14 (CNGC14) module links cytosolic auxin perception to Ca2+ influx upstream of growth inhibition.
Intrinsic adenylyl cyclase/guanylyl cyclase activity in auxin receptors integrates cyclic nucleotides into hormone signaling. AFB1-derived cGMP potentially activates CNGC14 for root growth inhibition.
These discoveries redefine auxin–Ca2+ crosstalk as a central paradigm in rapid growth regulation.
https://www.cell.com/trends/plant-science/fulltext/S1360-1385(26)00249-9
