Breast cancer drugs interact with gut microbiota to modulate efficacy

Gastrointestinal tract bacterial impact on breast cancer therapeutic outcomes is an emerging area of research. 

Microbiota is known to modify pharmacokinetics of chemotherapy and endocrine-targeting therapies and alter drug efficacy and toxicity profiles. Microbiota can also regulate systemic inflammation and immune responses and influence the effectiveness of both conventional and immunotherapeutic strategies for the treatment of breast cancer.

The bidirectional interactions between the gut microbiome and breast cancer therapies are still being studied, its impact is increasingly recognized.

The researchers are also exploring the personalized therapeutic strategies to harness the microbiome to improve breast cancer treatment outcomes.

https://www.embopress.org/doi/full/10.1038/s44321-024-00185-0

https://sciencemission.com/Gut-microbiota-interact-with-breast-cancer-therapeutics