The neuronal-like behavior of macrophages

Muscle spindle macrophages regulate sensorimotor homeostasis and metabolism. They express neuron-like gene expression signatures and support muscle contraction by releasing glutamate

The authors discuss the role of muscle spindle macrophages in controlling sensorimotor function in disease states.

The researchers discuss the Implications of neurotransmitter release by myeloid cells for neural circuitry in development, aging, and disease states in the central nervous system.

https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(25)00091-1

https://sciencemission.com/neuronal-like-behavior-of-macrophages