Epigenetic mechanisms in melanoma development and progression

Epigenetics alterations define gene and protein function Epigenetic changes affect the crosstalk between the tumor and its microenvironment, including the stroma and immune system components. 

Tumor resistance to therapy is often driven by epigenetic events.

Tumor propensity to metastasize is governed by epigenetic changes.

Epigenetic changes identified by advanced technologies may enable novel therapeutic modalities.

https://www.cell.com/trends/cancer/fulltext/S2405-8033(25)00099-8

https://sciencemission.com/Epigenetic-mechanisms-in-melanoma