Gelatin nanotraps for interleukin-6 sequestration in inflammation cell models

With their inherent biocompatibility and biodegradability, protein-derived biomaterials offer significant untapped potential as building blocks in molecular imprinting. 

Gelatin methacryloyl (GelMA) was successfully used to create bioinspired nanotraps designed to target the proinflammatory cytokine interleukin 6 (IL-6).

In vitro, the GelMA nanotraps effectively sequestered IL-6 in an inflammation cell model in a dose–response relationship.

Combining molecular imprinting and protein-derived biomaterials represents a biotechnological innovation to develop functional bio-nanomaterials tailored to suit specific biological applications.

https://www.cell.com/trends/biotechnology/fulltext/S0167-7799(25)00039-3

https://sciencemission.com/Protein-based-molecular-imprinting