Gut microbiome development in preterm infants

Preterm neonates undergo numerous interventions. 

The researchers characterize gut microbiome dynamics over the first 3 months of life in 236 preterm infants hospitalized.

They use multi-omics to show that antibiotics and other drugs alter gut microbiome development, but prenatal factors do not.

The authors observe low-diversity gut microbiome in neonates who develop necrotizing enterocolitis after day of life 40.

https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(24)00286-5

https://sciencemission.ayurmatrika.com/Clinical-sequelae-of-gut-microbiome-development-and-disruption-in-hospitalized-preterm-infants