Promotion of cell division by ER-mitochondria contacts!

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Promotion of cell division by ER-mitochondria contacts!

The researchers describe a mechanism by which mitochondrial Ca2+ regulates the metaphase-anaphase transition through  lamin B receptor (LBR) -mediated mitosis-specific ERmitochondria contact sites (ERMCSs).

The LBR-mediated ERMCSs promote the mitochondrial Ca2+ influx surge, which is essential for expanded energy generation during mitosis.

https://www.cell.com/cell-reports/fulltext/S2211-1247(24)01145-8

https://sciencemission.ayurmatrika.com/Mitotic-ER-mitochondria-contact-enhances-mitochondrial-Ca2-influx-to-promote-cell-division