Psychedelic brain’s emotional dynamics
The impact of psychedelics on emotional processing and mood is suggested to be a key driver of clinical efficacy.
Empirical evidence on the effect of psychedelics on negative and positive emotions is inconsistent, potentially due to limited granularity in emotional measurement.
Temporal dynamics in biological and behavioral measures of mood and emotion may have important implications for therapeutic support.
Psychedelics may promote emotional flexibility by modulating emotion regulation strategies, but their effects may differ between clinical and non-clinical populations.
Further research is needed on the interplay between challenging experiences, coping strategies, and emotional breakthroughs. Additionally, neural plasticity may enable affective plasticity, but more research is needed to pinpoint circuitlevel adaptations.
https://www.cell.com/trends/cognitive-sciences/fulltext/S1364-6613(25)00201-3
