Gut microbiota and eating behaviour in circadian syndrome
The gut microbiota undergoes diurnal oscillations, regulated by feeding schedules, timing, and the host’s internal clocks, thereby exerting a profound influence on metabolic health.
The bidirectional interaction between microbiota and circadian rhythms impacts feeding behaviour and metabolic homeostasis. The generation of microbiota-derived metabolites, including short-chain fatty acids, also exhibits diurnal oscillations, and modulates the enteroendocrine signalling and central regulation of appetite.
Disrupted circadian rhythms and poor dietary habits can trigger detrimental cycles that worsen metabolic risks, with the microbiota acting as a key communicator in this temporal dialogue.
Directing interventions towards the gut microbiota holds promising potential in reinstating circadian rhythms and improving eating behaviours, thereby leading to overall enhancements in metabolic health.
https://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(24)00189-9
