Next-generation immune profiling for immunotherapies
Emerging immune profiling technologies, such as high-dimensional single-cell cytometry, single-cell RNA sequencing, and spatial transcriptomics, enable unprecedented insights into the immune microenvironment of hematological malignancies.
Immune environment signatures are linked to therapy responses in large B cell lymphoma, acute myeloid leukemia, and multiple myeloma.
Advanced immune profiling complements traditional cancer cell focused diagnostic methods, improving disease classification, prognostication, and personalized treatment.
Integrating immune landscape assessments into clinical practice could refine therapeutic decisions and promote precision medicine in blood cancers.
https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(25)00144-3
