Publications

Therapeutic targeting of the cGAS-STING pathway in human disease

Therapeutic targeting of the cGAS-STING pathway in huma...

54

Targeted Protein Degradation of NUDT5 Dissociates Catalytic Inhibition from Protein Loss in 6-Thioguanine Response

Targeted Protein Degradation of NUDT5 Dissociates Catal...

41

Procognitive restoration of PV neuron plasticity in neurodevelopmental disorders

Procognitive restoration of PV neuron plasticity in neu...

50

The unfolded protein sensor IRE1 is essential for homeostatic dendritic cell maturation

The unfolded protein sensor IRE1 is essential for homeo...

40

Biallelic hexose-6-phosphate dehydrogenase variants cause mitochondrial dysfunction underlying Parkinson’s disease

Biallelic hexose-6-phosphate dehydrogenase variants cau...

35

Blood metabolomic signatures linking air pollution to lung cancer in the Cancer Prevention Studies

Blood metabolomic signatures linking air pollution to l...

44

Folic acid prevention of neural tube defects requires retinoic acid produced by ALDH1L1

Folic acid prevention of neural tube defects requires r...

47

Painful neuromas exhibit axonal phenotypic shift via nociceptive and mechanosensitive marker up-regulation

Painful neuromas exhibit axonal phenotypic shift via no...

43

Lysosomal dysfunction drives a transcriptional and epigenetic signature found in disease-associated microglia in neurodegenerative diseases

Lysosomal dysfunction drives a transcriptional and epig...

50

Human heart valve-like tissues from pluripotent stem cells with enhanced maturation recapitulate inflammatory valve disease

Human heart valve-like tissues from pluripotent stem ce...

48

The structural basis for LRRK2’s activation and autoinhibition

The structural basis for LRRK2’s activation and autoinh...

2052

GDF15 suppresses liver inflammation independently of weight loss through neuroendocrine glucocorticoid signaling

GDF15 suppresses liver inflammation independently of we...

42

Green light relieves stress-induced anxiety-like behaviors via visual-to-prefrontal projections in mice

Green light relieves stress-induced anxiety-like behavi...

101

Histological aging signatures for monitoring tissue-specific aging and disease

Histological aging signatures for monitoring tissue-spe...

79

Large-scale discovery, analysis and design of protein energy landscapes

Large-scale discovery, analysis and design of protein e...

58

What Is Hantavirus?

What Is Hantavirus?

58

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