Endometriosis and obesity interplay!
Body composition remarkably influences endometriosis, with both low body mass index (BMI) and obesity driving disease progression via distinct metabolic and inflammatory mechanisms.
Obesity-associated leptin signaling fuels systemic inflammation, angiogenesis, and ectopic lesion persistence in endometriosis, presenting novel therapeutic targets.
Shared molecular pathways between endometriosis and obesity provide a foundation for precision medicine approaches.
Emerging therapies targeting inflammation and metabolic dysfunction offer promising strategies for improved endometriosis management.
https://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(25)00056-6
