Immune organoids in biology!

There is a need for a good immune models to study interaction B and T cells with the lymphoid organs such as spleen, lymph nodes, and tonsils.
In this review, the researchers discuss versatile human tonsil/adenoid tissue-based ex vivo immune organoid cultures..
These platforms help in analyses of human B and T cell-mediated immune responses and support mechanistic studies as well as drug and vaccine testing in a human-first approach.
https://www.embopress.org/doi/full/10.1038/s44321-025-00193-8