Metabolite regulation of epigenetics in cancer
Epigenetic and metabolic alterations occur frequently in cancer cells.
The researchers present the concept that metabolite regulation of gene expression represents an evolutionary conserved mechanism.
They also review how individual metabolites affect epigenetic enzymes and cancer development, and discuss the opportunity for therapeutic targeting of metabolite-epigenetic regulation in cancer therapy.
https://www.cell.com/cell-reports/fulltext/S2211-1247(24)01166-5
https://sciencemission.ayurmatrika.com/Metabolite-regulation-of-epigenetics-in-cancer