Neuroglia in Neurodegeneration
In addition to neurons, during neurodegeneration. neuroglia-astrocytes, microglia, and oligodendrocytes also play crucial role in the pathogenesis and progression.
In this review, the authors discuss the protective and potentially harmful functions of glial cells in Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and other neurodegenerative disorders.
They also examine neuro-glial interactions in metabolic coupling, neuroinflammation, and protein aggregation.
The researchers also review the role of extracellular vesicles in disease propagation, epigenetic regulation of glial function, and the application of artificial intelligence in glial biology.
They also explore the glial-focused therapeutics to treat neurodegenerative diseases,
