Transcription elongation factors in diseases

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Transcription elongation factors in diseases

The elongation phase of transcription by RNA polymerase II is a regulatory hub in gene expression. 

There is growing complexity in the molecular mechanisms that control transcription elongation in mammalian cells.

The number of factors associated with transcription elongation has increased significantly.

Elongation factors are associated with a broad range of human diseases, particularly neurological diseases.

Elongation factors have emerged as potential therapeutic targets for various diseases.

https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(26)00163-7

https://sciencemission.com/Transcription-elongation