Understanding glycan function
Glycans (complex carbohydrates) are one of the four major classes of biological macromolecules, yet their functions remain substantially less understood than others, despite their importance in all biologies.
Defining glycan structure–function relationships remains one of the central unresolved challenges in glycobiology.
Glycomics extends far beyond glycoproteins and encompasses glycans associated with lipids, proteoglycans, and free oligosaccharides, including milk oligosaccharides and plant polysaccharides.
Mechanistic understanding of glycan function requires the integration of analytical, biological, structural, and computational approaches.
https://www.cell.com/trends/biochemical-sciences/fulltext/S0968-0004(26)00322-1
