How dietary soy shapes the microbiome and provides gut protection?
Diet impacts gut microbes and, subsequently, host immunity, but our understanding of the mechanisms driving this axis remains incomplete.
The researchers show that dietary soy promotes colonization of commensals like Limosilactobacillus reuteri and Muribaculum intestinale that cooperatively induce Tfh cells and polyreactive IgA in Peyer’s patches.
This polyreactive IgA maintains gut microbiota homeostasis and confers protection against Salmonella infection.
https://www.cell.com/immunity/fulltext/S1074-7613(26)00175-5
