How mitochondrial DNA leave mitochondria?
The presence of mitochondrial DNA (mtDNA) in the cytosol has been documented in the recent studies but the mechanisms of mtDNA release is not yet clear.
mtDNA is located in the mitochondrial matrix and cannot be released through the same pathways as intermembrane space proteins.
This article examines various processes and mechanisms involved in mtDNA release in the cytosol.
https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(25)00146-1
