The spinal cord vasculature in development and pathophysiology
In brain, retina, and spinal cord the vasculature plays an active role as regulator of homeostasis and repair, but vascular cells adopt region-specific traits
However, vascular organization and properties of spinal cord remain understudied.
Although it is assumed that spinal cord and brain neurovascular systems are built and function in the same way, the
researchers challenge this view by examining specific properties underlying spinal cord vascular development, physiology, and pathology.
They highlight unique angioarchitecture and homeostatic mechanisms, and discuss how neurovascular disruption contributes to spinal disorders and regenerative failure after injury.
