Cancer metabolism hijacked by brain
Cancers systemically exploit the nervous system through direct contacts, paracrine signaling, and intermediary cell mediated communication.
Tumors co-opt neuronal metabolic pathways to acquire nutrients and energy, supporting their growth and survival under stress.
Neuron-derived signals rewires tumor and immune/stromal cell metabolism, driving cancer progression.
Targeting neuro–tumor metabolic circuits offers therapeutic potential to disrupt cancer progression and treatment resistance.
https://www.cell.com/trends/cancer/fulltext/S2405-8033(25)00280-8
