Diet-microbiome interactions in cancer

Microbiomes residing in mucosal surfaces and within the tumor microenvironment may play a crucial role in the development and progression of tumors. 

Diet may also modulate tumors in multiple ways and thus understanding mechanistic interplay between diet-microbiome-host interactions enable to develop precision nutritional interventions impacting cancer development, dissemination, and treatment responses. But nutritional strategies integrating diet-microbiome interactions are not extensively used in cancer prevention and treatment regimen.

The researchers in this review discuss the effect of dietary composition on cancer related processes via alterations in microbiome. They also highlight how dietary timing, including time-restricted feeding, impacts microbial function in modulating cancer and its therapy.

They also evaluate the nutritional approaches that may enhance cancer treatment responsiveness and prospects in integrating diet-microbiome interactions into precision oncology.

https://www.cell.com/cancer-cell/fulltext/S1535-6108(25)00114-X?

https://sciencemission.com/Diet-microbiome-interactions-in-cancer