Environmental Risk Factors for Parkinson’s Disease

Identifying risk factors of PD would be essential to prevent the age - related disease.

Environmental factors, especially pesticides, trichloroethylene (TCE), and air pollution have been associated with PD.

The authors in this review evaluate the epidemiological and biological evidence on the associations of these factors with PD and review evidence on whether these putative associations are causal.

Due to the long lag between relevant exposures and the incidence of manifest PD, it is difficult to determine whether these associations are causal or not. But, if evidence  is considered in tandem with complementary research lines (such as animal models), it is increasingly likely that these associations reflect harmful causal effects.

The authors believe that the current evidence base is sufficiently strong enough to support call for stronger policy action.

https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.30067

https://sciencemission.com/Environmental-Risk-Factors-for-PD