Regulating rescue behavior!
Although brain regions in rescue behavior have been identified, the neural mechanisms involved are not well understood.
The role of hippocampus in memory, spatial navigation, emotional and social processing is well documented but its involvement in prosocial behavior is unclear.
The researchers show that exposure to a stressful context promotes the acquisition of rescue behavior in mice and that the dorsal hippocampus (dHPC) but not the ventral HPC (vHPC) is required for this learning.
Calcium imaging reveals synchronized neuronal ensembles in the dHPC that mechanistically support successful prosocial rescues.
https://www.cell.com/cell-reports/fulltext/S2211-1247(26)00001-X
