Subcutaneous adipose tissue and skeletal muscle mitochondria following weight loss
Bariatric surgery and dieting have distinct effects on mitochondrial metabolism in adipose tissue and skeletal muscle.
In adipose tissue, bariatric surgery may preserve or enhance mitochondrial metabolism, whereas dieting tends to reduce it.
In skeletal muscle, bariatric surgery may increase mitochondrial metabolism, but it typically remains unchanged after dieting.
Dieting in combination with exercise, rather than dieting alone, plays a pivotal role in activating muscle mitochondria. Adipose tissue shows greater responsiveness to weight loss interventions compared with skeletal muscle in terms of mitochondrial metabolism.
#sciencenewshighlights #ScienceMission
https://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(24)00221-2
