Engineered bacterial biofilms for biotechnological applications
Engineered bacterial biofilms genetically repurpose adhesion, matrix formation, spatial organization, and stress tolerance for defined beneficial functions.
Advances in synthetic biology, materials engineering, sensing, and computation now enable biofilm traits to be redirected for biotechnology.
An engineering framework based on biofilm life cycle links chassis, genetic programming, material surface, and biofilm formation and deployment.
Translation requires improved genetic stability, mass-transfer control, material durability, monitoring, scalability, biocontainment, and reproducibility.
Recent examples span bioproduction, biosensing, remediation, agriculture, therapeutic delivery, and engineered living materials.
https://www.cell.com/trends/biotechnology/fulltext/S0167-7799(26)00243-X
