Degeneration of pontine and medullary neurons
Degeneration of pontine and medullary neurons in Parkinson’s disease.
A neuronal circuit originating in the brainstem pons and medulla strongly induces REM sleep, even in awake mice.
Moreover, a subpopulation of neurons within this circuit is lost in patients with Parkinson’s disease, a neurodegenerative disease characterized by severe REM sleep abnormalities.
