How sleep protects against neurodegeneration
Cognitive dysfunction and Alzheimer's disease are associated with sleep loss but the precise mechanisms of sleep disturbances leading to neurodegeneration are not fully understood.
It is also not clear why some individuals are more susceptible to these effects than others.
This review discusses if sleep disturbances precede or result from neurodegenerative diseases and the functional significance of sleep changes during the preclinical disease phase.
The authors also discuss the potential role of sleep homeostasis as an adaptive mechanism enhancing resilience against cognitive decline and neurodegeneration.
https://www.cell.com/neuron/fulltext/S0896-6273(25)00117-5
https://sciencemission.com/sleep-protects-against-neurodegeneration
