Membrane-permeable trehalose 6-phosphate precursor spray increases wheat yields in field trials

In plants, endogenous growth promotor trehalose 6-phosphate (T6P), when introduced as a sunlight-activated T6P signaling precursor, DMNB-T6P, acts in a plant-permeable manner increases wheat yield significantly. 

 The authors show that both under well-watered and water-stressed conditions over 4 years, DMNB-T6P stimulated yield at an order of magnitude larger than average annual genetic gains of three elite varieties without additional water or fertilizer.

Mechanistically, T6P increased CO2, fixation and linear electron flow, starchy endosperm volume, grain sieve tube development and upregulated genes for starch, amino acid and protein synthesis (‘sink’).

https://www.nature.com/articles/s41587-025-02611-1

https://sciencemission.com/T6P-precursor-spray-increases-wheat-yields