Eosinophils role in cancer
Eosinophils display important antitumorigenic activities in the tumor microenvironment (TME).
Increased peripheral blood and tissue eosinophilia is often observed in response to immunotherapy.
Emerging data highlight a key interaction between eosinophils and T cells, where eosinophils promote T cell migration into the TME.
Eosinophil–T cell interactions can be utilized to amplify CAR-T therapy.
Methodological advances and new genetic tools now enable to characterize and examine the functional activities of eosinophils in the TME.
https://www.cell.com/trends/cancer/fulltext/S2405-8033(25)00131-1
