Nanoparticles to engineer immunity

Immunometabolism is a major mechanism for controlling immune cell function and programming. 

Recent advances in nanoparticle (NP) technologies incorporate metabolites into degradable polymer backbones or loaded as NP cargo.

NP properties are easily modifiable to customize delivery, making them an attractive platform for metabolic engineering of immune cells.

 Metabolically active NPs can be delivered in vivo to target specific immune cells, such as monocytes and dendritic cells, for metabolic reprogramming to drive therapeutic benefit.

https://www.cell.com/trends/biotechnology/fulltext/S0167-7799(24)00345-7

https://sciencemission.com/Engineering-immunity-using-nanoparticles