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Taurine from tumour niche drives glycolysis to promote leukaemogenesis

Taurine from tumour niche drives glycolysis t...

 35

Sleep and the recovery from stress

Sleep and the recovery from stress

 112

Anatomy of the Cerebellum

Anatomy of the Cerebellum

 31

Anatomy of the Hippocampus

Anatomy of the Hippocampus

 40

Taurine from tumour niche drives glycolysis to promote leukaemogenesis

Taurine from tumour niche drives glycolysis t...

 35

Sleep and the recovery from stress

Sleep and the recovery from stress

 112

STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity

STAT5 and STAT3 balance shapes dendritic cell...

 38

Tissue mechanics in tumor heterogeneity and aggression

Tissue mechanics in tumor heterogeneity and a...

 44

An AAV capsid proposed as microglia-targeting directs genetic expression in forebrain excitatory neurons

An AAV capsid proposed as microglia-targeting...

 43

Minimally invasive, wide-field two-photon imaging of the brainstem at cellular resolution

Minimally invasive, wide-field two-photon ima...

 50

Quantitative PET imaging and modeling of molecular blood-brain barrier permeability

Quantitative PET imaging and modeling of mole...

 61

Species-resolved profiling of antibiotic resistance genes in complex metagenomes through long-read overlapping with Argo

Species-resolved profiling of antibiotic resi...

 87

Anatomy of the Cerebellum

Anatomy of the Cerebellum

 31

Anatomy of the Hippocampus

Anatomy of the Hippocampus

 40

Cerebral Cortex

Cerebral Cortex

 55

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

The Spinal Cord, Spinal Nerves, and Spinal Re...

 68

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGET...

 7510

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

 333

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

 327

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

 343

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Science Hangouts

Protein monoaminylation in brain: novel mechanisms of neural development, plasticity and disease
Science Hangouts

Protein monoaminylation in brain: novel mechanisms of neural development, plasticity and disease

 19422

Dynamics of  muscle stem cells in skeletal muscle homeostasis and repair
Science Hangouts

Dynamics of muscle stem cells in skeletal muscle homeostasis and repair

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The Science of Exercise
Science Hangouts

The Science of Exercise

 252

Cancer, Inflammation & Tissue Repair
Science Hangouts

Cancer, Inflammation & Tissue Repair

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Deubiquitinases in cell cycle and cancer
Science Hangouts

Deubiquitinases in cell cycle and cancer

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Circadian Rhythms, Nutrition and Metabolism
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Circadian Rhythms, Nutrition and Metabolism

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Local Translation and Generation of Novel Protein Isoforms in Astrocytes
Science Hangouts

Local Translation and Generation of Novel Protein Isoforms in Astrocytes

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Digestive Enzymes On the Loose: Autodigestion in Metabolic Disease, Shock and Death
Science Hangouts

Digestive Enzymes On the Loose: Autodigestion in Metabolic Disease, Shock and Death

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Targeting integrins with small molecules to cure cancer and lupus
Science Hangouts

Targeting integrins with small molecules to cure cancer and lupus

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Pain and Self-Fulfilling Prophesies
Science Hangouts

Pain and Self-Fulfilling Prophesies

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Science News Highlights

Sleep and the recovery from stress
News highlights

Sleep and the recovery from stress

 25

An AAV capsid targets excitatory neurons rather than microglia
News highlights

An AAV capsid targets excitatory neurons rather than m...

 18

Tumor heterogeneity and aggression
News highlights

Tumor heterogeneity and aggression

 19

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Tumor taurine drives glycolysis to promote leukaemogenesis

Tumor taurine drives glycolysis to promote leukaem...

 57

STAT5 and STAT3 balance shapes tumor immunity

STAT5 and STAT3 balance shapes tumor immunity

 62

Molecular signatures of frontotemporal lobar degeneration

Molecular signatures of frontotemporal lobar degen...

 45

Tracking the motions of GPCRs

Tracking the motions of GPCRs

 60

Impact of Alzheimer’s disease on the whole body

Impact of Alzheimer’s disease on the whole body

 68

How Type III CRISPR-Cas systems defend against viral infection?

How Type III CRISPR-Cas systems defend against vir...

 75

New stem cell model sheds light on human amniotic sac development

New stem cell model sheds light on human amniotic ...

 24

Mechanism of auxin influx in plants

Mechanism of auxin influx in plants

 38

AI & imaging technique to evaluate blood clots in heart disease

AI & imaging technique to evaluate blood clots in ...

 44

AI to expand the mitochondrial targeting toolkit

AI to expand the mitochondrial targeting toolkit

 113

How 2 proteins with opposite effect regulate huntingtin protein’s movement in neurons

How 2 proteins with opposite effect regulate hunti...

 25

AI-powered app enables anemia screening using fingernail selfies

AI-powered app enables anemia screening using fing...

 32

Programmable gene insertion in human cells using a new gene editor

Programmable gene insertion in human cells using a...

 79

Molecular signatures of frontotemporal lobar degeneration

Molecular signatures of frontotemporal lobar degen...

 45

Impact of Alzheimer’s disease on the whole body

Impact of Alzheimer’s disease on the whole body

 68

How 2 proteins with opposite effect regulate huntingtin protein’s movement in neurons

How 2 proteins with opposite effect regulate hunti...

 25

Modulating synapses through astrocytes

Modulating synapses through astrocytes

 151

Dopamine D1–D2 signalling in hippocampus arbitrates approach and avoidance

Dopamine D1–D2 signalling in hippocampus arbitrate...

 110

Identical signature of unconsciousness with different anesthetics

Identical signature of unconsciousness with differ...

 72

Mechanism to process past and future memories parallelly during sleep

Mechanism to process past and future memories para...

 91

Predicting progression of multiple sclerosis

Predicting progression of multiple sclerosis

 58

Role of physiological and pathological Aβ on synapses in human brain tissue

Role of physiological and pathological Aβ on synap...

 59

Clusterin protein alleviates Alzheimer’s disease-relevant processes

Clusterin protein alleviates Alzheimer’s disease-r...

 90

How brain weighs positive vs. negative social experience?

How brain weighs positive vs. negative social expe...

 181

Connection between autism spectrum disorder and myotonic dystrophy

Connection between autism spectrum disorder and my...

 64

Adolescents who sleep longer perform better at cognitive tasks

Adolescents who sleep longer perform better at cog...

 131

Tumor taurine drives glycolysis to promote leukaemogenesis

Tumor taurine drives glycolysis to promote leukaem...

 57

STAT5 and STAT3 balance shapes tumor immunity

STAT5 and STAT3 balance shapes tumor immunity

 62

Does brain cancer start at pregnancy?

Does brain cancer start at pregnancy?

 62

Zinc-transporting protein contributes to aggressive growth of brain tumor

Zinc-transporting protein contributes to aggressiv...

 102

Interplay between human genetics and intratumoral microbiota in colorectal cancer

Interplay between human genetics and intratumoral ...

 63

Ferroptosis induction by lysosomal lipid peroxidation

Ferroptosis induction by lysosomal lipid peroxidation

 151

Three-dimensional gene hubs may promote brain cancer

Three-dimensional gene hubs may promote brain cancer

 38

Targeting PIKfyve-driven lipid metabolism in pancreatic cancer

Targeting PIKfyve-driven lipid metabolism in pancr...

 68

Linking germline variants to cancer progression

Linking germline variants to cancer progression

 50

Tumor-derived erythropoietin acts as an immunosuppressive switch in cancer immunity

Tumor-derived erythropoietin acts as an immunosupp...

 138

Gut microbes release cancer-fighting bile acids that block hormone signals

Gut microbes release cancer-fighting bile acids th...

 207

CD36-dependent pathway to enhance cancer drug uptake

CD36-dependent pathway to enhance cancer drug uptake

 81

Gene fusion may cause explosive growth in chronic myeloid leukaemia

Gene fusion may cause explosive growth in chronic ...

 82

Tirzepatide's role in weight loss and metabolic health

Tirzepatide's role in weight loss and metabolic he...

 69

How molecular glues protect insulin-producing cells from diabetic damage

How molecular glues protect insulin-producing cell...

 135

Dramatic changes in liver metabolism during fasting

Dramatic changes in liver metabolism during fasting

 233

Obesity gene in dogs is also relevant to humans

Obesity gene in dogs is also relevant to humans

 148

Blood vessel inflammation from artificial sweetener

Blood vessel inflammation from artificial sweetener

 166

Adipose populations linked to metabolic health in obesity

Adipose populations linked to metabolic health in ...

 144

A light-sensitive brain protein, opsin 3, also regulates food consumption

A light-sensitive brain protein, opsin 3, also reg...

 178

Intermittent fasting could be unsafe for teenagers

Intermittent fasting could be unsafe for teenagers

 164

Mechanism of endothelial insulin resistance

Mechanism of endothelial insulin resistance

 168

Gut microbes link drinking sugary beverages and diabetes risk

Gut microbes link drinking sugary beverages and di...

 187

A ‘non-industrialized’ style diet can reduce risk of chronic disease

A ‘non-industrialized’ style diet can reduce risk ...

 172

Multi-omics identifies risk factors of childhood obesity

Multi-omics identifies risk factors of childhood o...

 166

Microbial regulation of bile acid signalling

Microbial regulation of bile acid signalling

 172

How Type III CRISPR-Cas systems defend against viral infection?

How Type III CRISPR-Cas systems defend against vir...

 75

AI & imaging technique to evaluate blood clots in heart disease

AI & imaging technique to evaluate blood clots in ...

 44

AI to expand the mitochondrial targeting toolkit

AI to expand the mitochondrial targeting toolkit

 113

AI-powered app enables anemia screening using fingernail selfies

AI-powered app enables anemia screening using fing...

 32

Mapping centuries old genetic mutation that protects against HIV

Mapping centuries old genetic mutation that protec...

 51

AI uncovers antiviral compounds using limited data!

AI uncovers antiviral compounds using limited data!

 78

AI identifies PHGDH as amyloid pathology driver in Alzheimer’s disease

AI identifies PHGDH as amyloid pathology driver in...

 141

AI tool to better assess Parkinson’s disease, other movement disorders

AI tool to better assess Parkinson’s disease, othe...

 72

AI tool can track effectiveness of multiple sclerosis treatments

AI tool can track effectiveness of multiple sclero...

 75

AI to improve diagnosis of drug-resistant infections

AI to improve diagnosis of drug-resistant infections

 91

AI models of the brain could serve as ‘digital twins’ in research

AI models of the brain could serve as ‘digital twi...

 124

Pain relief with designer cannabinoids without adverse effects

Pain relief with designer cannabinoids without adv...

 128

Newly discovered weight loss peptide without side effects

Newly discovered weight loss peptide without side ...

 309

Programmable gene insertion in human cells using a new gene editor

Programmable gene insertion in human cells using a...

 79

New lipid nanoparticle platform delivers mRNA to the brain through the blood-brain barrier

New lipid nanoparticle platform delivers mRNA to t...

 212

Microfluidic protocol to extract and purify DNA

Microfluidic protocol to extract and purify DNA

 120

Artificial sensing system using synthetic neurons

Artificial sensing system using synthetic neurons

 178

The nanoparticle-based vaccine against many variants of SARS-CoV-2

The nanoparticle-based vaccine against many varian...

 122

Nanoparticle-based itaconate treatment for atherosclerotic plaque resolution

Nanoparticle-based itaconate treatment for atheros...

 155

A lipid nanoparticle delivers mRNA cure for pre-eclampsia

A lipid nanoparticle delivers mRNA cure for pre-ec...

 154

‘Supercharging’ T cells with mitochondria enhances their antitumor activity

‘Supercharging’ T cells with mitochondria enhances...

 159

Can we ‘recharge’ our cells?

Can we ‘recharge’ our cells?

 168

How can alterations in metabolism encode specific transcriptional instructions

How can alterations in metabolism encode specific t...

 66

Growing chimpanzee naive-type pluripotent stem cells for the first time

Growing chimpanzee naive-type pluripotent stem cel...

 116

Aging-related blood disorders from supercharged mitochondria

Aging-related blood disorders from supercharged mi...

 89

New neurons may reverse damage in Huntington’s disease

New neurons may reverse damage in Huntington’s dis...

 82

Placenta-derived factor promotes the expansion of liver progenitor cells

Placenta-derived factor promotes the expansion of ...

 66

Human assembloid model of the ascending neural sensory pathway

Human assembloid model of the ascending neural sen...

 61

How gut cells respond to bacterial toxins

How gut cells respond to bacterial toxins

 255

Mechanisms of aging in Meibomian gland

Mechanisms of aging in Meibomian gland

 121

Stem cells based circadian drug delivery

Stem cells based circadian drug delivery

 118

How healthy stem cells turn into oral cancer

How healthy stem cells turn into oral cancer

 104

Lifelong maintenance of intestinal stem cells

Lifelong maintenance of intestinal stem cells

 107

How neural stem cells are activated in the adult human brain

How neural stem cells are activated in the adult h...

 134

The maternal microbiome during pregnancy impacts offspring’s stem cells in mice

The maternal microbiome during pregnancy impacts o...

 153

ITSN1 gene linked to substantial risk of Parkinson’s disease

ITSN1 gene linked to substantial risk of Parkinson...

 113

Disordered renal metabolism in myotonic dystrophy type 1

Disordered renal metabolism in myotonic dystrophy ...

 112

Gene ‘silencer’ in junk DNA prevents fatal neurological disease

Gene ‘silencer’ in junk DNA prevents fatal neurolo...

 90

The role of moms X chromosome in cognition and aging of daughter

The role of moms X chromosome in cognition and agi...

 95

Genes for depression across ethnicities

Genes for depression across ethnicities

 106

Gene editing extends lifespan in mouse model of prion disease

Gene editing extends lifespan in mouse model of pr...

 100

Two new gene variants linked to epilepsy identified!

Two new gene variants linked to epilepsy identified!

 132

Dysregulation of mTOR signalling is a converging mechanism in lissencephaly

Dysregulation of mTOR signalling is a converging m...

 128

The role of rare germline structural variants in pediatric solid tumors

The role of rare germline structural variants in p...

 120

Linking genetic risk for schizophrenia to a malformed skull

Linking genetic risk for schizophrenia to a malfor...

 108

New mutation linked to early-onset Parkinsonism

New mutation linked to early-onset Parkinsonism

 135

Combination therapy to treat glioma

Combination therapy to treat glioma

 115

How unique metabolism protects naked mole rats from heart attacks

How unique metabolism protects naked mole rats fro...

 118

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

 145

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

 127

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

 130

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

 138

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

 126

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

 127

Role of ECM in brain memory

Role of ECM in brain memory

 120

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

 128

Supramolecular anticoagulants with on-demand reversibility

Supramolecular anticoagulants with on-demand rever...

 134

Cell vulnerability 'fingerprint' related to Parkinson's identified!

Cell vulnerability 'fingerprint' related to Parkin...

 126

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

 127

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

 119

Gut bacteria produced compounds can treat inflammation

Gut bacteria produced compounds can treat inflamma...

 122

TMEM65 regulates mitochondrial calcium efflux

TMEM65 regulates mitochondrial calcium efflux

 69

Inhibition of ceramide synthesis contributes to cardiometabolic diseases

Inhibition of ceramide synthesis contributes to ca...

 65

How a Y chromosome gene may shape the course of heart valve disease

How a Y chromosome gene may shape the course of he...

 185

Why babies recover, but adults scar, after heart damage

Why babies recover, but adults scar, after heart d...

 96

Testosterone increases damage following a heart attack

Testosterone increases damage following a heart at...

 96

The structure of apolipoprotein B100 from human low-density lipoprotein

The structure of apolipoprotein B100 from human lo...

 109

Blood vessel lumen formation and maintenance

Blood vessel lumen formation and maintenance

 137

First noninvasive method to continually measure true blood pressure

First noninvasive method to continually measure tr...

 126

A glutamine metabolic switch in red blood cell development and disease

A glutamine metabolic switch in red blood cell dev...

 152

Protein kinase N promotes cardiac fibrosis in heart failure

Protein kinase N promotes cardiac fibrosis in hear...

 129

Role of lipids in regulating cardiac arrhythmias

Role of lipids in regulating cardiac arrhythmias

 174

Temperature-controlled calcium channel, CatSper activates sperm

Temperature-controlled calcium channel, CatSper ac...

 51

How mothers adapt to the metabolic demands of nursing

How mothers adapt to the metabolic demands of nursing

 62

A protein complex critical to male fertility uncovered!

A protein complex critical to male fertility uncov...

 89

Association between placental DNA methylation and schizophrenia

Association between placental DNA methylation and ...

 466

Interactions between sex hormones and neurological health

Interactions between sex hormones and neurological...

 144

Cell-free DNA shed from the placenta during pregnancy predicts preeclampsia

Cell-free DNA shed from the placenta during pregna...

 116

Communication between body muscle and the brain influences fertility

Communication between body muscle and the brain in...

 121

Epigenetic programming in uterine fibroblasts regulate birth timing

Epigenetic programming in uterine fibroblasts regu...

 98

Grey matter (94%) in the brains of mothers undergoes changes during pregnancy

Grey matter (94%) in the brains of mothers undergo...

 112

Surges in estrogen promotes binge drinking in females

Surges in estrogen promotes binge drinking in females

 117

Extra X chromosome impairs the development of male fetal germ cells

Extra X chromosome impairs the development of male...

 127

Mothers massively change their intestines during pregnancy and nursing

Mothers massively change their intestines during p...

 144

A key transcription factor modulates expanded pluripotency in blastoids and blastocysts

A key transcription factor modulates expanded plur...

 121

How mRNA modification controls cellular stress response

How mRNA modification controls cellular stress res...

 294

A protein involved in autophagy of aggresomes identified!

A protein involved in autophagy of aggresomes iden...

 89

Eliminating excessive scarring during wound healing

Eliminating excessive scarring during wound healing

 85

Mechanism governing specific binding of EVs to recipient cells

Mechanism governing specific binding of EVs to rec...

 87

Circulating miR-126-3p is a biomarker for knee osteoarthritis

Circulating miR-126-3p is a biomarker for knee ost...

 69

Synthetic lethal interactions among DNA repair factors

Synthetic lethal interactions among DNA repair fac...

 47

Tool to analyze protein turnover in a single cell

Tool to analyze protein turnover in a single cell

 57

Fetal anemia linked to mitochondrial protein synthesis deficiency

Fetal anemia linked to mitochondrial protein synth...

 118

Small molecules restore mutant mitochondrial DNA polymerase activity

Small molecules restore mutant mitochondrial DNA p...

 96

Engineering smart delivery for gene editors

Engineering smart delivery for gene editors

 98

Improved method for producing designer proteins

Improved method for producing designer proteins

 131

New mechanism to relieve mitochondrial stress

New mechanism to relieve mitochondrial stress

 153

Tracking material carried by extracellular vesicles (EVs)

Tracking material carried by extracellular vesicle...

 85

A new type of immune defense in E. coli

A new type of immune defense in E. coli

 59

A symbiotic gut fungus wards off liver disease in mice

A symbiotic gut fungus wards off liver disease in ...

 44

Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis

Nerve- and airway-associated interstitial macropha...

 88

First structural images of a tuberculosis-fighting virus

First structural images of a tuberculosis-fighting...

 94

Tool for tracking antibiotic resistance genes

Tool for tracking antibiotic resistance genes

 231

Brain linked stress and satiety modulators in pathogen infection induced sickness behaviors

Brain linked stress and satiety modulators in path...

 68

Fiber consumption protects gut from serious bacterial infection

Fiber consumption protects gut from serious bacter...

 139

Mechanisms underlying antiviral immunity against phages

Mechanisms underlying antiviral immunity against p...

 113

Intestinal immune cell prevents food allergies

Intestinal immune cell prevents food allergies

 141

Cellular regulator of mRNA vaccine revealed!

Cellular regulator of mRNA vaccine revealed!

 161

Attenuated Mycobacterium tuberculosis vaccine candidate to prevent tuberculosis

Attenuated Mycobacterium tuberculosis vaccine cand...

 81

Regeneration of macrophage peroxisomes limit SARS-CoV-2 tissue inflammation

Regeneration of macrophage peroxisomes limit SARS-...

 167

COVID-19 neuro-inflammation from microglia dysfunction, neurovascular inflammation and focal neuropathologies

COVID-19 neuro-inflammation from microglia dysfunc...

 890

New stem cell model sheds light on human amniotic sac development

New stem cell model sheds light on human amniotic ...

 24

MicroRNAs guide the development of Purkinje cells

MicroRNAs guide the development of Purkinje cells

 136

Ancient viral DNA shapes early embryo development

Ancient viral DNA shapes early embryo development

 92

Mechanism to bring newborn neurons out of the neuronal nest

Mechanism to bring newborn neurons out of the neur...

 114

Leptin in neurodevelopment!

Leptin in neurodevelopment!

 128

Role of Integrator in early neural fate commitment

Role of Integrator in early neural fate commitment

 140

Impaired chaperonin function may cause brain malformations and seizures

Impaired chaperonin function may cause brain malfo...

 141

Role of protein netrin1 in spinal cord development

Role of protein netrin1 in spinal cord development

 129

Inhibiting metabolic enzyme to “pause" human development

Inhibiting metabolic enzyme to “pause" human devel...

 135

Human-specific genes regulate key gene mutated in autism spectrum disorders

Human-specific genes regulate key gene mutated in ...

 126

Physiological role of 5-formylcytosine (5fC) epigenetic marker in the embryonic development

Physiological role of 5-formylcytosine (5fC) epige...

 127

Mechanism of auxin influx in plants

Mechanism of auxin influx in plants

 38

Plant-based protein is linked to a longer life

Plant-based protein is linked to a longer life

 56

Epigenetic marker is essential for Marchantia sperm function

Epigenetic marker is essential for Marchantia sper...

 79

Anti-bacterial role of plant metabolite

Anti-bacterial role of plant metabolite

 110

Key genes to fight against crop parasites identified!

Key genes to fight against crop parasites identified!

 78

CoQ10-producing rice with gene editing

CoQ10-producing rice with gene editing

 94

Bacteria used to amplify plant hormones

Bacteria used to amplify plant hormones

 98

Protein protects biological nitrogen fixation from oxidative stress

Protein protects biological nitrogen fixation from...

 104

Plant roots change their growth pattern during ‘puberty’

Plant roots change their growth pattern during ‘pu...

 134

The biosynthesis of steroidal defense metabolites in plants

The biosynthesis of steroidal defense metabolites ...

 131

Decoding plant-to-fungi communication

Decoding plant-to-fungi communication

 137

Stopping plants from passing viruses to their progeny

Stopping plants from passing viruses to their progeny

 126

How female gametes control fertilization recovery in flowering plants

How female gametes control fertilization recovery ...

 132

Why vaccination site matters for immune response

Why vaccination site matters for immune response

 157

Broadly neutralizing human antibodies to neutralize snake venom

Broadly neutralizing human antibodies to neutraliz...

 57

Lactate links metabolism and epigenetics for trained immunity

Lactate links metabolism and epigenetics for train...

 92

Predicting relapse of autoimmune small vessel vasculitis

Predicting relapse of autoimmune small vessel vasc...

 100

Asian Immune Diversity Atlas

Asian Immune Diversity Atlas

 41

Acetylcholine structure reveals mechanisms that cause autoimmune disease

Acetylcholine structure reveals mechanisms that ca...

 109

Peacekeeper cells protect the body from autoimmunity during infection

Peacekeeper cells protect the body from autoimmuni...

 217

Ginger compound with potential to treat inflammatory bowel disease

Ginger compound with potential to treat inflammato...

 112

Intercellular mRNA transfer alters the human pluripotent stem cell state

Intercellular mRNA transfer alters the human pluri...

 89

A treatment-resistant, severe type of asthma successfully modeled in mice

A treatment-resistant, severe type of asthma succe...

 86

How Tregs control the immune system

How Tregs control the immune system

 109

Opioid delta-receptor agonists alleviate stress-induced irritable bowel syndrome symptoms

Opioid delta-receptor agonists alleviate stress-in...

 87

Activation of the entire complement cascade in inflammatory and autoimmune diseases

Activation of the entire complement cascade in inf...

 98

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

 54

Printed skin to replace animal testing

Printed skin to replace animal testing

 66

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

 80

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

 87

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

 100

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

 129

Tracking the motions of GPCRs

Tracking the motions of GPCRs

 60

The structure of human sweetness

The structure of human sweetness

 85

Innovative deep-brain imaging to study brainstem structures

Innovative deep-brain imaging to study brainstem s...

 107

RNA blood test to detect cancers

RNA blood test to detect cancers

 86

EXPLORER total body PET scanner may help detect brain disease

EXPLORER total body PET scanner may help detect br...

 55

Simulating multilayered protein condensates support learning and memory

Simulating multilayered protein condensates suppor...

 71

Structural insight into mitochondrial pyruvate carrier

Structural insight into mitochondrial pyruvate car...

 78

Cell membranes sustain phospholipid imbalance via cholesterol asymmetry

Cell membranes sustain phospholipid imbalance via ...

 219

Nonlinear sound-sheet microscopy

Nonlinear sound-sheet microscopy

 69

Hearing triggered by molecular “spring”

Hearing triggered by molecular “spring”

 74

“Ball and chain” mechanism inactivates calcium-activated potassium channel

“Ball and chain” mechanism inactivates calcium-act...

 99

Tool for RNA tertiary structure prediction

Tool for RNA tertiary structure prediction

 178

How molecules navigate the nuclear pore complex

How molecules navigate the nuclear pore complex

 109

How the brain regulates emotions

How the brain regulates emotions

 127

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

 114

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

 120

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

 142

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

 121

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

 141

Link between dietary choices and brain health

Link between dietary choices and brain health

 114

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

 141

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

 162

Males burn more fat, while females recycle it during exercise

Males burn more fat, while females recycle it duri...

 126

Paternal dietary macronutrient balance and energy intake drive metabolic and behavioral differences among offspring

Paternal dietary macronutrient balance and energy ...

 114

Research

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Taurine from tumour niche drives glycolysis to promote leukaemogenesis

Taurine from tumour niche drives glycolysis to pro...

 35

Sleep and the recovery from stress

Sleep and the recovery from stress

 112

Anatomy of the Cerebellum

Anatomy of the Cerebellum

 31

Anatomy of the Hippocampus

Anatomy of the Hippocampus

 40

Cerebral Cortex

Cerebral Cortex

 55

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

 68

STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity

STAT5 and STAT3 balance shapes dendritic cell func...

 38

An AAV capsid proposed as microglia-targeting directs genetic expression in forebrain excitatory neurons

An AAV capsid proposed as microglia-targeting dire...

 43

Tissue mechanics in tumor heterogeneity and aggression

Tissue mechanics in tumor heterogeneity and aggres...

 44

Restoration of intestinal secondary bile acid synthesis: A potential approach to improve pancreatic β cell function in type 1 diabetes

Restoration of intestinal secondary bile acid synt...

 58

Repurposing glucose-lowering drugs for cancer therapy

Repurposing glucose-lowering drugs for cancer therapy

 66

Selection on the epigenome: small RNA inheritance in animal evolution

Selection on the epigenome: small RNA inheritance ...

 32

Multi-site investigation of gut microbiota in CDKL5 deficiency disorder mouse models: Targeting dysbiosis to improve neurological outcomes

Multi-site investigation of gut microbiota in CDKL...

 41

Taurine from tumour niche drives glycolysis to promote leukaemogenesis

Taurine from tumour niche drives glycolysis to pro...

 35

Sleep and the recovery from stress

Sleep and the recovery from stress

 112

STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity

STAT5 and STAT3 balance shapes dendritic cell func...

 38

Tissue mechanics in tumor heterogeneity and aggression

Tissue mechanics in tumor heterogeneity and aggres...

 44

Restoration of intestinal secondary bile acid synthesis: A potential approach to improve pancreatic β cell function in type 1 diabetes

Restoration of intestinal secondary bile acid synt...

 58

Repurposing glucose-lowering drugs for cancer therapy

Repurposing glucose-lowering drugs for cancer therapy

 66

Selection on the epigenome: small RNA inheritance in animal evolution

Selection on the epigenome: small RNA inheritance ...

 32

Multi-site investigation of gut microbiota in CDKL5 deficiency disorder mouse models: Targeting dysbiosis to improve neurological outcomes

Multi-site investigation of gut microbiota in CDKL...

 41

Post-gastrulation amnioids as a stem cell-derived model of human extra-embryonic development

Post-gastrulation amnioids as a stem cell-derived ...

 26

Structural insights into auxin influx mediated by the Arabidopsis AUX1

Structural insights into auxin influx mediated by ...

 23

A neuronal Slit1-dependent program rescues oligodendrocyte differentiation and myelination under chronic hypoxic conditions

A neuronal Slit1-dependent program rescues oligode...

 28

Direct evaluation of antiplatelet therapy in coronary artery disease by comprehensive image-based profiling of circulating platelets

Direct evaluation of antiplatelet therapy in coron...

 14

Rheumatoid arthritis synovial fluid induces JAK-dependent intracellular activation of human sensory neurons

Rheumatoid arthritis synovial fluid induces JAK-de...

 50

An AAV capsid proposed as microglia-targeting directs genetic expression in forebrain excitatory neurons

An AAV capsid proposed as microglia-targeting dire...

 43

Minimally invasive, wide-field two-photon imaging of the brainstem at cellular resolution

Minimally invasive, wide-field two-photon imaging ...

 50

Quantitative PET imaging and modeling of molecular blood-brain barrier permeability

Quantitative PET imaging and modeling of molecular...

 61

Species-resolved profiling of antibiotic resistance genes in complex metagenomes through long-read overlapping with Argo

Species-resolved profiling of antibiotic resistanc...

 87

Integrated analysis of transcriptional and metabolic responses to mitochondrial stress

Integrated analysis of transcriptional and metabol...

 79

DNA methylation entropy is a biomarker for aging

DNA methylation entropy is a biomarker for aging

 149

Engineered nucleocytosolic vehicles for loading of programmable editors

Engineered nucleocytosolic vehicles for loading of...

 73

A cysteine-less and ultra-fast split intein rationally engineered from being aggregation-prone to highly efficient in protein trans-splicing

A cysteine-less and ultra-fast split intein ration...

 79

MetaFlowTrain: a highly parallelized and modular fluidic system for studying exometabolite-mediated inter-organismal interactions

MetaFlowTrain: a highly parallelized and modular f...

 42

Harnessing human iPSC-microglia for CNS-wide delivery of disease-modifying proteins

Harnessing human iPSC-microglia for CNS-wide deliv...

 64

Protocol for the fabrication of self-standing (nano)cellulose-based 3D scaffolds for tissue engineering

Protocol for the fabrication of self-standing (nan...

 58

Polycystins recruit cargo to distinct ciliary extracellular vesicle subtypes in C. elegans

Polycystins recruit cargo to distinct ciliary extr...

 75

MARIGOLD and MitoCIAO, two searchable compendia to visualize and functionalize protein complexes during mitochondrial remodeling

MARIGOLD and MitoCIAO, two searchable compendia to...

 110

Anatomy of the Cerebellum

Anatomy of the Cerebellum

 31

Anatomy of the Hippocampus

Anatomy of the Hippocampus

 40

Cerebral Cortex

Cerebral Cortex

 55

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

 68

Protein Digestion and Absorption

Protein Digestion and Absorption

 532

AlphaFold: for Protein Structure Prediction

AlphaFold: for Protein Structure Prediction

 156

Protein structure, classification, functions, properties of proteins

Protein structure, classification, functions, prop...

 251

Post Translation Modification

Post Translation Modification

 276

Protein Translation

Protein Translation

 163

Transcription, Transcription Factors, and  Chromatin Remodeling

Transcription, Transcription Factors, and Chromat...

 262

AMINO ACIDS CLASSIFICATION  AND  PROPERTIES

AMINO ACIDS CLASSIFICATION AND PROPERTIES

 317

DNA replication

DNA replication

 193

DNA Repair

DNA Repair

 227

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

 7510

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

 333

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

 327

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

 343

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

 117

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

 111

HEAD AND NECK CANCER

HEAD AND NECK CANCER

 116

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

 113

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

 118

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

 122

School Science

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Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 86

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 94

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 90

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 258

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 203

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 131

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 134

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 119

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 148

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 129

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 146

APOE in Alzheimer’s

APOE in Alzheimer’s

 149

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 247

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 258

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 203

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 131

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 134

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 119

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 148

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 129

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 146

APOE in Alzheimer’s

APOE in Alzheimer’s

 149

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 247

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

 132

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

 155

Presenilin (PSEN)  in Alzheimer’s

Presenilin (PSEN)  in Alzheimer’s

 99

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 86

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 94

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 90

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