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All Publications Protocols Presentations Posters
Emerging approaches to enhance human brain organoid physiology

Emerging approaches to enhance human brain or...

 16

Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition

Alpha-synuclein mutations mislocalize cytopla...

 25

Gene context drift identifies drug targets to mitigate cancer treatment resistance

Gene context drift identifies drug targets to...

 14

Spatiotemporal orchestration of mitosis by cyclin-dependent kinase

Spatiotemporal orchestration of mitosis by cy...

 7

Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition

Alpha-synuclein mutations mislocalize cytopla...

 25

Spatiotemporal orchestration of mitosis by cyclin-dependent kinase

Spatiotemporal orchestration of mitosis by cy...

 7

RIFINs displayed on malaria-infected erythrocytes bind KIR2DL1 and KIR2DS1

RIFINs displayed on malaria-infected erythroc...

 11

Dysfunctional mitochondria trap proteins in the intermembrane space

Dysfunctional mitochondria trap proteins in t...

 30

Emerging approaches to enhance human brain organoid physiology

Emerging approaches to enhance human brain or...

 16

Gene context drift identifies drug targets to mitigate cancer treatment resistance

Gene context drift identifies drug targets to...

 14

Improving predictability, reliability, and generalizability of brain-wide associations for cognitive abilities via multimodal stacking

Improving predictability, reliability, and ge...

 28

Glycine-to-aspartic acid mutation at codon 51 in Snca disrupts the synaptic localisation of α-synuclein and enhances its propensity for synucleinopathy

Glycine-to-aspartic acid mutation at codon 51...

 30

Anatomy of the Cerebellum

Anatomy of the Cerebellum

 95

Anatomy of the Hippocampus

Anatomy of the Hippocampus

 137

Cerebral Cortex

Cerebral Cortex

 125

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

The Spinal Cord, Spinal Nerves, and Spinal Re...

 124

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGET...

 9857

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

 379

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

 361

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

 386

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Science Hangouts

Protein monoaminylation in brain: novel mechanisms of neural development, plasticity and disease
Science Hangouts

Protein monoaminylation in brain: novel mechanisms of neural development, plasticity and disease

 21171

Dynamics of  muscle stem cells in skeletal muscle homeostasis and repair
Science Hangouts

Dynamics of muscle stem cells in skeletal muscle homeostasis and repair

 308

The Science of Exercise
Science Hangouts

The Science of Exercise

 271

Cancer, Inflammation & Tissue Repair
Science Hangouts

Cancer, Inflammation & Tissue Repair

 262

Deubiquitinases in cell cycle and cancer
Science Hangouts

Deubiquitinases in cell cycle and cancer

 243

Circadian Rhythms, Nutrition and Metabolism
Science Hangouts

Circadian Rhythms, Nutrition and Metabolism

 321

Local Translation and Generation of Novel Protein Isoforms in Astrocytes
Science Hangouts

Local Translation and Generation of Novel Protein Isoforms in Astrocytes

 287

Digestive Enzymes On the Loose: Autodigestion in Metabolic Disease, Shock and Death
Science Hangouts

Digestive Enzymes On the Loose: Autodigestion in Metabolic Disease, Shock and Death

 454

Targeting integrins with small molecules to cure cancer and lupus
Science Hangouts

Targeting integrins with small molecules to cure cancer and lupus

 332

Pain and Self-Fulfilling Prophesies
Science Hangouts

Pain and Self-Fulfilling Prophesies

 363

Science News Highlights

Enhancing human brain organoid physiology
News highlights

Enhancing human brain organoid physiology

 7

How alpha-synuclein mutations cause Parkinson’s pathology
News highlights

How alpha-synuclein mutations cause Parkinson’s pathology

 3

New tool identifies drug targets to stop cancer treatment resistance
News highlights

New tool identifies drug targets to stop cancer treatm...

 6

News

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Controlling mitosis by cyclin-dependent kinase

Controlling mitosis by cyclin-dependent kinase

 17

Betaine as an exercise mimetic for aging protection

Betaine as an exercise mimetic for aging protection

 45

How immune cells fight – and are fooled by – malaria

How immune cells fight – and are fooled by – malaria

 38

Senescence-resistant human mesenchymal progenitor cells counter aging

Senescence-resistant human mesenchymal progenitor ...

 44

Fixing cholesterol metabolism problem to prevent blindness

Fixing cholesterol metabolism problem to prevent b...

 25

Predicting cognitive abilities from brain scans

Predicting cognitive abilities from brain scans

 30

GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity

GRK-biased adrenergic agonists for the treatment o...

 54

Oncogene mutation in colorectal cancer leads to metabolic reprogramming

Oncogene mutation in colorectal cancer leads to me...

 41

Alzheimer’s protective mutation works by taming inflammation in the brain

Alzheimer’s protective mutation works by taming in...

 50

An innovative drug for controlling weight and blood sugar

An innovative drug for controlling weight and bloo...

 113

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

 32

Switch-like gene expression modulates disease risk

Switch-like gene expression modulates disease risk

 38

How micronutrients taken up by our body

How micronutrients taken up by our body

 131

Meal-related memory in ventral hippocampus

Meal-related memory in ventral hippocampus

 22

Reward experience map in flexible hippocampal population

Reward experience map in flexible hippocampal popu...

 32

Neuroprosthesis for instantaneous voice-synthesis

Neuroprosthesis for instantaneous voice-synthesis

 49

ELAV protein shapes the brain’s unique circular RNA landscape

ELAV protein shapes the brain’s unique circular RN...

 58

Neurons associated with the suppression of binge drinking identified!

Neurons associated with the suppression of binge d...

 61

How the brain allows us to infer emotions

How the brain allows us to infer emotions

 42

How the brain forms habits and why they are so hard to break

How the brain forms habits and why they are so har...

 95

Molecular signatures of frontotemporal lobar degeneration

Molecular signatures of frontotemporal lobar degen...

 78

Impact of Alzheimer’s disease on the whole body

Impact of Alzheimer’s disease on the whole body

 95

How 2 proteins with opposite effect regulate huntingtin protein’s movement in neurons

How 2 proteins with opposite effect regulate hunti...

 53

Modulating synapses through astrocytes

Modulating synapses through astrocytes

 182

Dopamine D1–D2 signalling in hippocampus arbitrates approach and avoidance

Dopamine D1–D2 signalling in hippocampus arbitrate...

 134

Identical signature of unconsciousness with different anesthetics

Identical signature of unconsciousness with differ...

 93

Oncogene mutation in colorectal cancer leads to metabolic reprogramming

Oncogene mutation in colorectal cancer leads to me...

 41

HPV drives tumor development in rare nasal cancers

HPV drives tumor development in rare nasal cancers

 26

Tumor taurine drives glycolysis to promote leukaemogenesis

Tumor taurine drives glycolysis to promote leukaem...

 97

STAT5 and STAT3 balance shapes tumor immunity

STAT5 and STAT3 balance shapes tumor immunity

 108

Does brain cancer start at pregnancy?

Does brain cancer start at pregnancy?

 96

Zinc-transporting protein contributes to aggressive growth of brain tumor

Zinc-transporting protein contributes to aggressiv...

 134

Interplay between human genetics and intratumoral microbiota in colorectal cancer

Interplay between human genetics and intratumoral ...

 83

Ferroptosis induction by lysosomal lipid peroxidation

Ferroptosis induction by lysosomal lipid peroxidation

 180

Three-dimensional gene hubs may promote brain cancer

Three-dimensional gene hubs may promote brain cancer

 65

Targeting PIKfyve-driven lipid metabolism in pancreatic cancer

Targeting PIKfyve-driven lipid metabolism in pancr...

 87

Linking germline variants to cancer progression

Linking germline variants to cancer progression

 74

Tumor-derived erythropoietin acts as an immunosuppressive switch in cancer immunity

Tumor-derived erythropoietin acts as an immunosupp...

 166

Gut microbes release cancer-fighting bile acids that block hormone signals

Gut microbes release cancer-fighting bile acids th...

 228

GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity

GRK-biased adrenergic agonists for the treatment o...

 54

An innovative drug for controlling weight and blood sugar

An innovative drug for controlling weight and bloo...

 113

How maternal obesity also affects the next generation

How maternal obesity also affects the next generation

 40

A potential treatment for obesity-linked breathing disorder

A potential treatment for obesity-linked breathing...

 31

Tirzepatide's role in weight loss and metabolic health

Tirzepatide's role in weight loss and metabolic he...

 89

How molecular glues protect insulin-producing cells from diabetic damage

How molecular glues protect insulin-producing cell...

 166

Dramatic changes in liver metabolism during fasting

Dramatic changes in liver metabolism during fasting

 260

Obesity gene in dogs is also relevant to humans

Obesity gene in dogs is also relevant to humans

 175

Blood vessel inflammation from artificial sweetener

Blood vessel inflammation from artificial sweetener

 186

Adipose populations linked to metabolic health in obesity

Adipose populations linked to metabolic health in ...

 165

A light-sensitive brain protein, opsin 3, also regulates food consumption

A light-sensitive brain protein, opsin 3, also reg...

 205

Intermittent fasting could be unsafe for teenagers

Intermittent fasting could be unsafe for teenagers

 187

Mechanism of endothelial insulin resistance

Mechanism of endothelial insulin resistance

 196

Predicting cognitive abilities from brain scans

Predicting cognitive abilities from brain scans

 30

TACIT algorithm to diagnose and treat cancer

TACIT algorithm to diagnose and treat cancer

 31

N-acyl lipids in biology!

N-acyl lipids in biology!

 45

Generative AI to design RNA

Generative AI to design RNA

 71

How Type III CRISPR-Cas systems defend against viral infection?

How Type III CRISPR-Cas systems defend against vir...

 106

AI & imaging technique to evaluate blood clots in heart disease

AI & imaging technique to evaluate blood clots in ...

 71

AI to expand the mitochondrial targeting toolkit

AI to expand the mitochondrial targeting toolkit

 141

AI-powered app enables anemia screening using fingernail selfies

AI-powered app enables anemia screening using fing...

 60

Mapping centuries old genetic mutation that protects against HIV

Mapping centuries old genetic mutation that protec...

 77

AI uncovers antiviral compounds using limited data!

AI uncovers antiviral compounds using limited data!

 100

AI identifies PHGDH as amyloid pathology driver in Alzheimer’s disease

AI identifies PHGDH as amyloid pathology driver in...

 172

AI tool to better assess Parkinson’s disease, other movement disorders

AI tool to better assess Parkinson’s disease, othe...

 94

AI tool can track effectiveness of multiple sclerosis treatments

AI tool can track effectiveness of multiple sclero...

 95

Programmable gene insertion in human cells using a new gene editor

Programmable gene insertion in human cells using a...

 105

New lipid nanoparticle platform delivers mRNA to the brain through the blood-brain barrier

New lipid nanoparticle platform delivers mRNA to t...

 241

Microfluidic protocol to extract and purify DNA

Microfluidic protocol to extract and purify DNA

 134

Artificial sensing system using synthetic neurons

Artificial sensing system using synthetic neurons

 198

The nanoparticle-based vaccine against many variants of SARS-CoV-2

The nanoparticle-based vaccine against many varian...

 152

Nanoparticle-based itaconate treatment for atherosclerotic plaque resolution

Nanoparticle-based itaconate treatment for atheros...

 173

A lipid nanoparticle delivers mRNA cure for pre-eclampsia

A lipid nanoparticle delivers mRNA cure for pre-ec...

 170

‘Supercharging’ T cells with mitochondria enhances their antitumor activity

‘Supercharging’ T cells with mitochondria enhances...

 171

Can we ‘recharge’ our cells?

Can we ‘recharge’ our cells?

 182

Senescence-resistant human mesenchymal progenitor cells counter aging

Senescence-resistant human mesenchymal progenitor ...

 44

Glial replacement therapy slows Huntington’s disease

Glial replacement therapy slows Huntington’s disease

 48

A rapid method for building vascular organoids

A rapid method for building vascular organoids

 38

Platform for in vitro production of human microglia cells from iPSC

Platform for in vitro production of human microgli...

 67

How can alterations in metabolism encode specific transcriptional instructions

How can alterations in metabolism encode specific t...

 82

Growing chimpanzee naive-type pluripotent stem cells for the first time

Growing chimpanzee naive-type pluripotent stem cel...

 138

Aging-related blood disorders from supercharged mitochondria

Aging-related blood disorders from supercharged mi...

 110

New neurons may reverse damage in Huntington’s disease

New neurons may reverse damage in Huntington’s dis...

 103

Placenta-derived factor promotes the expansion of liver progenitor cells

Placenta-derived factor promotes the expansion of ...

 87

Human assembloid model of the ascending neural sensory pathway

Human assembloid model of the ascending neural sen...

 81

How gut cells respond to bacterial toxins

How gut cells respond to bacterial toxins

 275

Mechanisms of aging in Meibomian gland

Mechanisms of aging in Meibomian gland

 141

Stem cells based circadian drug delivery

Stem cells based circadian drug delivery

 137

ITSN1 gene linked to substantial risk of Parkinson’s disease

ITSN1 gene linked to substantial risk of Parkinson...

 133

Disordered renal metabolism in myotonic dystrophy type 1

Disordered renal metabolism in myotonic dystrophy ...

 132

Gene ‘silencer’ in junk DNA prevents fatal neurological disease

Gene ‘silencer’ in junk DNA prevents fatal neurolo...

 106

The role of moms X chromosome in cognition and aging of daughter

The role of moms X chromosome in cognition and agi...

 112

Genes for depression across ethnicities

Genes for depression across ethnicities

 132

Gene editing extends lifespan in mouse model of prion disease

Gene editing extends lifespan in mouse model of pr...

 110

Two new gene variants linked to epilepsy identified!

Two new gene variants linked to epilepsy identified!

 144

Dysregulation of mTOR signalling is a converging mechanism in lissencephaly

Dysregulation of mTOR signalling is a converging m...

 155

The role of rare germline structural variants in pediatric solid tumors

The role of rare germline structural variants in p...

 132

Linking genetic risk for schizophrenia to a malformed skull

Linking genetic risk for schizophrenia to a malfor...

 120

New mutation linked to early-onset Parkinsonism

New mutation linked to early-onset Parkinsonism

 151

Combination therapy to treat glioma

Combination therapy to treat glioma

 127

How unique metabolism protects naked mole rats from heart attacks

How unique metabolism protects naked mole rats fro...

 130

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

 158

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

 141

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

 143

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

 150

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

 137

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

 139

Role of ECM in brain memory

Role of ECM in brain memory

 134

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

 141

Supramolecular anticoagulants with on-demand reversibility

Supramolecular anticoagulants with on-demand rever...

 146

Cell vulnerability 'fingerprint' related to Parkinson's identified!

Cell vulnerability 'fingerprint' related to Parkin...

 142

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

 139

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

 130

Gut bacteria produced compounds can treat inflammation

Gut bacteria produced compounds can treat inflamma...

 133

Fixing cholesterol metabolism problem to prevent blindness

Fixing cholesterol metabolism problem to prevent b...

 25

Similarities between atherosclerotic blood vessels and tumor development

Similarities between atherosclerotic blood vessels...

 57

TMEM65 regulates mitochondrial calcium efflux

TMEM65 regulates mitochondrial calcium efflux

 90

Inhibition of ceramide synthesis contributes to cardiometabolic diseases

Inhibition of ceramide synthesis contributes to ca...

 84

How a Y chromosome gene may shape the course of heart valve disease

How a Y chromosome gene may shape the course of he...

 201

Why babies recover, but adults scar, after heart damage

Why babies recover, but adults scar, after heart d...

 112

Testosterone increases damage following a heart attack

Testosterone increases damage following a heart at...

 109

The structure of apolipoprotein B100 from human low-density lipoprotein

The structure of apolipoprotein B100 from human lo...

 129

Blood vessel lumen formation and maintenance

Blood vessel lumen formation and maintenance

 156

First noninvasive method to continually measure true blood pressure

First noninvasive method to continually measure tr...

 138

A glutamine metabolic switch in red blood cell development and disease

A glutamine metabolic switch in red blood cell dev...

 164

Protein kinase N promotes cardiac fibrosis in heart failure

Protein kinase N promotes cardiac fibrosis in hear...

 140

Role of lipids in regulating cardiac arrhythmias

Role of lipids in regulating cardiac arrhythmias

 190

High blood pressure in pregnancy linked to increased risk of seizure in children

High blood pressure in pregnancy linked to increas...

 39

Iron in sex determination of mammalian embryos

Iron in sex determination of mammalian embryos

 48

Temperature-controlled calcium channel, CatSper activates sperm

Temperature-controlled calcium channel, CatSper ac...

 78

How mothers adapt to the metabolic demands of nursing

How mothers adapt to the metabolic demands of nursing

 81

A protein complex critical to male fertility uncovered!

A protein complex critical to male fertility uncov...

 106

Association between placental DNA methylation and schizophrenia

Association between placental DNA methylation and ...

 489

Interactions between sex hormones and neurological health

Interactions between sex hormones and neurological...

 166

Cell-free DNA shed from the placenta during pregnancy predicts preeclampsia

Cell-free DNA shed from the placenta during pregna...

 136

Communication between body muscle and the brain influences fertility

Communication between body muscle and the brain in...

 150

Epigenetic programming in uterine fibroblasts regulate birth timing

Epigenetic programming in uterine fibroblasts regu...

 124

Grey matter (94%) in the brains of mothers undergoes changes during pregnancy

Grey matter (94%) in the brains of mothers undergo...

 132

Surges in estrogen promotes binge drinking in females

Surges in estrogen promotes binge drinking in females

 134

Extra X chromosome impairs the development of male fetal germ cells

Extra X chromosome impairs the development of male...

 152

Controlling mitosis by cyclin-dependent kinase

Controlling mitosis by cyclin-dependent kinase

 17

Switch-like gene expression modulates disease risk

Switch-like gene expression modulates disease risk

 38

Maintaining optimal pH within the Golgi apparatus

Maintaining optimal pH within the Golgi apparatus

 121

How cells untie DNA to protect the genome

How cells untie DNA to protect the genome

 35

Polysaccharide assembly and transport in Pseudomonas aeruginosa biofilm

Polysaccharide assembly and transport in Pseudomon...

 96

Reexamining binding determinants of a receptor linked to sepsis

Reexamining binding determinants of a receptor lin...

 40

How mRNA modification controls cellular stress response

How mRNA modification controls cellular stress res...

 340

A protein involved in autophagy of aggresomes identified!

A protein involved in autophagy of aggresomes iden...

 109

Eliminating excessive scarring during wound healing

Eliminating excessive scarring during wound healing

 98

Mechanism governing specific binding of EVs to recipient cells

Mechanism governing specific binding of EVs to rec...

 112

Circulating miR-126-3p is a biomarker for knee osteoarthritis

Circulating miR-126-3p is a biomarker for knee ost...

 88

Synthetic lethal interactions among DNA repair factors

Synthetic lethal interactions among DNA repair fac...

 65

Tool to analyze protein turnover in a single cell

Tool to analyze protein turnover in a single cell

 81

How immune cells fight – and are fooled by – malaria

How immune cells fight – and are fooled by – malaria

 38

Immune tolerance to gut microbes is initiated by a key bacterial sensor

Immune tolerance to gut microbes is initiated by a...

 52

New antibodies against current and future coronaviruses identified!

New antibodies against current and future coronavi...

 39

When bacteria get hungry, they kill – and eat – their neighbors

When bacteria get hungry, they kill – and eat – th...

 236

Jaundice-associated pigment in protecting against malaria

Jaundice-associated pigment in protecting against ...

 33

Bioenergetic trigger accelerating antibiotic resistance

Bioenergetic trigger accelerating antibiotic resis...

 37

How microbiota protects against influenza in newborns

How microbiota protects against influenza in newborns

 82

SARS-CoV-2 protein found to spread between cells, triggering immune attack on healthy cells

SARS-CoV-2 protein found to spread between cells, ...

 956

Lipid-based communication between body and gut microbes to maintain intestinal health

Lipid-based communication between body and gut mic...

 84

A new type of immune defense in E. coli

A new type of immune defense in E. coli

 83

A symbiotic gut fungus wards off liver disease in mice

A symbiotic gut fungus wards off liver disease in ...

 62

Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis

Nerve- and airway-associated interstitial macropha...

 113

First structural images of a tuberculosis-fighting virus

First structural images of a tuberculosis-fighting...

 118

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

 32

New stem cell model sheds light on human amniotic sac development

New stem cell model sheds light on human amniotic ...

 47

MicroRNAs guide the development of Purkinje cells

MicroRNAs guide the development of Purkinje cells

 154

Ancient viral DNA shapes early embryo development

Ancient viral DNA shapes early embryo development

 116

Mechanism to bring newborn neurons out of the neuronal nest

Mechanism to bring newborn neurons out of the neur...

 140

Leptin in neurodevelopment!

Leptin in neurodevelopment!

 144

Role of Integrator in early neural fate commitment

Role of Integrator in early neural fate commitment

 153

Impaired chaperonin function may cause brain malformations and seizures

Impaired chaperonin function may cause brain malfo...

 158

Role of protein netrin1 in spinal cord development

Role of protein netrin1 in spinal cord development

 138

Inhibiting metabolic enzyme to “pause" human development

Inhibiting metabolic enzyme to “pause" human devel...

 145

Human-specific genes regulate key gene mutated in autism spectrum disorders

Human-specific genes regulate key gene mutated in ...

 141

Physiological role of 5-formylcytosine (5fC) epigenetic marker in the embryonic development

Physiological role of 5-formylcytosine (5fC) epige...

 143

Mechanism of auxin influx in plants

Mechanism of auxin influx in plants

 59

Plant-based protein is linked to a longer life

Plant-based protein is linked to a longer life

 83

Epigenetic marker is essential for Marchantia sperm function

Epigenetic marker is essential for Marchantia sper...

 96

Anti-bacterial role of plant metabolite

Anti-bacterial role of plant metabolite

 132

Key genes to fight against crop parasites identified!

Key genes to fight against crop parasites identified!

 95

CoQ10-producing rice with gene editing

CoQ10-producing rice with gene editing

 110

Bacteria used to amplify plant hormones

Bacteria used to amplify plant hormones

 119

Protein protects biological nitrogen fixation from oxidative stress

Protein protects biological nitrogen fixation from...

 129

Plant roots change their growth pattern during ‘puberty’

Plant roots change their growth pattern during ‘pu...

 142

The biosynthesis of steroidal defense metabolites in plants

The biosynthesis of steroidal defense metabolites ...

 146

Decoding plant-to-fungi communication

Decoding plant-to-fungi communication

 155

Stopping plants from passing viruses to their progeny

Stopping plants from passing viruses to their progeny

 136

How female gametes control fertilization recovery in flowering plants

How female gametes control fertilization recovery ...

 145

Betaine as an exercise mimetic for aging protection

Betaine as an exercise mimetic for aging protection

 45

Alzheimer’s protective mutation works by taming inflammation in the brain

Alzheimer’s protective mutation works by taming in...

 50

Heterogeneity in immune cell abnormalities in patients with systemic sclerosis

Heterogeneity in immune cell abnormalities in pati...

 42

Why vaccination site matters for immune response

Why vaccination site matters for immune response

 187

Broadly neutralizing human antibodies to neutralize snake venom

Broadly neutralizing human antibodies to neutraliz...

 77

Lactate links metabolism and epigenetics for trained immunity

Lactate links metabolism and epigenetics for train...

 119

Predicting relapse of autoimmune small vessel vasculitis

Predicting relapse of autoimmune small vessel vasc...

 118

Asian Immune Diversity Atlas

Asian Immune Diversity Atlas

 61

Acetylcholine structure reveals mechanisms that cause autoimmune disease

Acetylcholine structure reveals mechanisms that ca...

 131

Peacekeeper cells protect the body from autoimmunity during infection

Peacekeeper cells protect the body from autoimmuni...

 237

Ginger compound with potential to treat inflammatory bowel disease

Ginger compound with potential to treat inflammato...

 128

Intercellular mRNA transfer alters the human pluripotent stem cell state

Intercellular mRNA transfer alters the human pluri...

 112

A treatment-resistant, severe type of asthma successfully modeled in mice

A treatment-resistant, severe type of asthma succe...

 99

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

 71

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

 67

Printed skin to replace animal testing

Printed skin to replace animal testing

 84

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

 91

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

 99

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

 110

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

 141

How micronutrients taken up by our body

How micronutrients taken up by our body

 131

Imaging-based STAMP technique for single-cell RNA analysis

Imaging-based STAMP technique for single-cell RNA ...

 31

Tracking the motions of GPCRs

Tracking the motions of GPCRs

 92

The structure of human sweetness

The structure of human sweetness

 113

Innovative deep-brain imaging to study brainstem structures

Innovative deep-brain imaging to study brainstem s...

 131

RNA blood test to detect cancers

RNA blood test to detect cancers

 102

EXPLORER total body PET scanner may help detect brain disease

EXPLORER total body PET scanner may help detect br...

 76

Simulating multilayered protein condensates support learning and memory

Simulating multilayered protein condensates suppor...

 87

Structural insight into mitochondrial pyruvate carrier

Structural insight into mitochondrial pyruvate car...

 95

Cell membranes sustain phospholipid imbalance via cholesterol asymmetry

Cell membranes sustain phospholipid imbalance via ...

 240

Nonlinear sound-sheet microscopy

Nonlinear sound-sheet microscopy

 88

Hearing triggered by molecular “spring”

Hearing triggered by molecular “spring”

 91

“Ball and chain” mechanism inactivates calcium-activated potassium channel

“Ball and chain” mechanism inactivates calcium-act...

 110

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

 33

How the brain regulates emotions

How the brain regulates emotions

 141

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

 129

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

 136

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

 159

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

 137

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

 152

Link between dietary choices and brain health

Link between dietary choices and brain health

 126

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

 155

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

 185

Males burn more fat, while females recycle it during exercise

Males burn more fat, while females recycle it duri...

 138

Paternal dietary macronutrient balance and energy intake drive metabolic and behavioral differences among offspring

Paternal dietary macronutrient balance and energy ...

 133

Research

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Emerging approaches to enhance human brain organoid physiology

Emerging approaches to enhance human brain organoi...

 16

Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition

Alpha-synuclein mutations mislocalize cytoplasmic ...

 25

Gene context drift identifies drug targets to mitigate cancer treatment resistance

Gene context drift identifies drug targets to miti...

 14

Spatiotemporal orchestration of mitosis by cyclin-dependent kinase

Spatiotemporal orchestration of mitosis by cyclin-...

 7

RIFINs displayed on malaria-infected erythrocytes bind KIR2DL1 and KIR2DS1

RIFINs displayed on malaria-infected erythrocytes ...

 11

Dysfunctional mitochondria trap proteins in the intermembrane space

Dysfunctional mitochondria trap proteins in the in...

 30

Gastric cancer: from biomarkers to functional precision medicine

Gastric cancer: from biomarkers to functional prec...

 55

The estrous cycle modulates hippocampal spine dynamics, dendritic processing, and spatial coding

The estrous cycle modulates hippocampal spine dyna...

 21

The gut microbiota promotes pain in fibromyalgia

The gut microbiota promotes pain in fibromyalgia

 32

Apolipoprotein M attenuates age-related macular degeneration phenotypes via sphingosine-1-phosphate signaling and lysosomal lipid catabolism

Apolipoprotein M attenuates age-related macular de...

 21

Rapid group-2 innate lymphoid cell mobilization from the intestine aids in early lung defense and repair

Rapid group-2 innate lymphoid cell mobilization fr...

 39

Immunotherapy-related cognitive impairment after CAR T cell therapy in mice

Immunotherapy-related cognitive impairment after C...

 40

Improving predictability, reliability, and generalizability of brain-wide associations for cognitive abilities via multimodal stacking

Improving predictability, reliability, and general...

 28

Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition

Alpha-synuclein mutations mislocalize cytoplasmic ...

 25

Spatiotemporal orchestration of mitosis by cyclin-dependent kinase

Spatiotemporal orchestration of mitosis by cyclin-...

 7

RIFINs displayed on malaria-infected erythrocytes bind KIR2DL1 and KIR2DS1

RIFINs displayed on malaria-infected erythrocytes ...

 11

Dysfunctional mitochondria trap proteins in the intermembrane space

Dysfunctional mitochondria trap proteins in the in...

 30

Gastric cancer: from biomarkers to functional precision medicine

Gastric cancer: from biomarkers to functional prec...

 55

The estrous cycle modulates hippocampal spine dynamics, dendritic processing, and spatial coding

The estrous cycle modulates hippocampal spine dyna...

 21

The gut microbiota promotes pain in fibromyalgia

The gut microbiota promotes pain in fibromyalgia

 32

Apolipoprotein M attenuates age-related macular degeneration phenotypes via sphingosine-1-phosphate signaling and lysosomal lipid catabolism

Apolipoprotein M attenuates age-related macular de...

 21

Rapid group-2 innate lymphoid cell mobilization from the intestine aids in early lung defense and repair

Rapid group-2 innate lymphoid cell mobilization fr...

 39

Immunotherapy-related cognitive impairment after CAR T cell therapy in mice

Immunotherapy-related cognitive impairment after C...

 40

GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity

GRK-biased adrenergic agonists for the treatment o...

 22

KRAS G12V mutation-selective requirement for ACSS2 in colorectal adenoma formation

KRAS G12V mutation-selective requirement for ACSS2...

 22

Fixed and flexible perceptual rhythms

Fixed and flexible perceptual rhythms

 19

Emerging approaches to enhance human brain organoid physiology

Emerging approaches to enhance human brain organoi...

 16

Gene context drift identifies drug targets to mitigate cancer treatment resistance

Gene context drift identifies drug targets to miti...

 14

Improving predictability, reliability, and generalizability of brain-wide associations for cognitive abilities via multimodal stacking

Improving predictability, reliability, and general...

 28

Glycine-to-aspartic acid mutation at codon 51 in Snca disrupts the synaptic localisation of α-synuclein and enhances its propensity for synucleinopathy

Glycine-to-aspartic acid mutation at codon 51 in S...

 30

Advancing nanopore technology toward protein identification and sequencing

Advancing nanopore technology toward protein ident...

 48

Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits

Enhancer AAV toolbox for accessing and perturbing ...

 42

Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC

Iterative transcription factor screening enables r...

 44

The microbiome diversifies long- to short-chain fatty acid-derived N-acyl lipids

The microbiome diversifies long- to short-chain fa...

 41

Generative and predictive neural networks for the design of functional RNA molecules

Generative and predictive neural networks for the ...

 56

An AAV capsid proposed as microglia-targeting directs genetic expression in forebrain excitatory neurons

An AAV capsid proposed as microglia-targeting dire...

 73

Minimally invasive, wide-field two-photon imaging of the brainstem at cellular resolution

Minimally invasive, wide-field two-photon imaging ...

 77

Quantitative PET imaging and modeling of molecular blood-brain barrier permeability

Quantitative PET imaging and modeling of molecular...

 87

Species-resolved profiling of antibiotic resistance genes in complex metagenomes through long-read overlapping with Argo

Species-resolved profiling of antibiotic resistanc...

 112

Anatomy of the Cerebellum

Anatomy of the Cerebellum

 95

Anatomy of the Hippocampus

Anatomy of the Hippocampus

 137

Cerebral Cortex

Cerebral Cortex

 125

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

 124

Protein Digestion and Absorption

Protein Digestion and Absorption

 546

AlphaFold: for Protein Structure Prediction

AlphaFold: for Protein Structure Prediction

 179

Protein structure, classification, functions, properties of proteins

Protein structure, classification, functions, prop...

 279

Post Translation Modification

Post Translation Modification

 292

Protein Translation

Protein Translation

 177

Transcription, Transcription Factors, and  Chromatin Remodeling

Transcription, Transcription Factors, and Chromat...

 278

AMINO ACIDS CLASSIFICATION  AND  PROPERTIES

AMINO ACIDS CLASSIFICATION AND PROPERTIES

 345

DNA replication

DNA replication

 211

DNA Repair

DNA Repair

 249

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

 9857

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

 379

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

 361

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

 386

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

 131

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

 121

HEAD AND NECK CANCER

HEAD AND NECK CANCER

 130

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

 124

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

 129

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

 134

School Science

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Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 99

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 110

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 110

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 280

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 216

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 144

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 150

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 131

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 160

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 135

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 160

APOE in Alzheimer’s

APOE in Alzheimer’s

 158

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 261

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 280

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 216

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 144

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 150

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 131

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 160

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 135

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 160

APOE in Alzheimer’s

APOE in Alzheimer’s

 158

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 261

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

 147

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

 171

Presenilin (PSEN)  in Alzheimer’s

Presenilin (PSEN)  in Alzheimer’s

 113

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 99

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 110

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 110

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