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All Publications Protocols Presentations Posters
Emerging approaches to enhance human brain organoid physiology

Emerging approaches to enhance human brain or...

 31

Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition

Alpha-synuclein mutations mislocalize cytopla...

 37

Gene context drift identifies drug targets to mitigate cancer treatment resistance

Gene context drift identifies drug targets to...

 18

Spatiotemporal orchestration of mitosis by cyclin-dependent kinase

Spatiotemporal orchestration of mitosis by cy...

 10

Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition

Alpha-synuclein mutations mislocalize cytopla...

 37

Spatiotemporal orchestration of mitosis by cyclin-dependent kinase

Spatiotemporal orchestration of mitosis by cy...

 10

RIFINs displayed on malaria-infected erythrocytes bind KIR2DL1 and KIR2DS1

RIFINs displayed on malaria-infected erythroc...

 22

Dysfunctional mitochondria trap proteins in the intermembrane space

Dysfunctional mitochondria trap proteins in t...

 34

Emerging approaches to enhance human brain organoid physiology

Emerging approaches to enhance human brain or...

 31

Gene context drift identifies drug targets to mitigate cancer treatment resistance

Gene context drift identifies drug targets to...

 18

Improving predictability, reliability, and generalizability of brain-wide associations for cognitive abilities via multimodal stacking

Improving predictability, reliability, and ge...

 33

Glycine-to-aspartic acid mutation at codon 51 in Snca disrupts the synaptic localisation of α-synuclein and enhances its propensity for synucleinopathy

Glycine-to-aspartic acid mutation at codon 51...

 33

Anatomy of the Cerebellum

Anatomy of the Cerebellum

 99

Anatomy of the Hippocampus

Anatomy of the Hippocampus

 140

Cerebral Cortex

Cerebral Cortex

 129

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

The Spinal Cord, Spinal Nerves, and Spinal Re...

 127

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGET...

 9897

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

 382

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

 364

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

 390

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Science Hangouts

Protein monoaminylation in brain: novel mechanisms of neural development, plasticity and disease
Science Hangouts

Protein monoaminylation in brain: novel mechanisms of neural development, plasticity and disease

 21186

Dynamics of  muscle stem cells in skeletal muscle homeostasis and repair
Science Hangouts

Dynamics of muscle stem cells in skeletal muscle homeostasis and repair

 309

The Science of Exercise
Science Hangouts

The Science of Exercise

 273

Cancer, Inflammation & Tissue Repair
Science Hangouts

Cancer, Inflammation & Tissue Repair

 264

Deubiquitinases in cell cycle and cancer
Science Hangouts

Deubiquitinases in cell cycle and cancer

 244

Circadian Rhythms, Nutrition and Metabolism
Science Hangouts

Circadian Rhythms, Nutrition and Metabolism

 323

Local Translation and Generation of Novel Protein Isoforms in Astrocytes
Science Hangouts

Local Translation and Generation of Novel Protein Isoforms in Astrocytes

 289

Digestive Enzymes On the Loose: Autodigestion in Metabolic Disease, Shock and Death
Science Hangouts

Digestive Enzymes On the Loose: Autodigestion in Metabolic Disease, Shock and Death

 456

Targeting integrins with small molecules to cure cancer and lupus
Science Hangouts

Targeting integrins with small molecules to cure cancer and lupus

 334

Pain and Self-Fulfilling Prophesies
Science Hangouts

Pain and Self-Fulfilling Prophesies

 364

Science News Highlights

Enhancing human brain organoid physiology
News highlights

Enhancing human brain organoid physiology

 10

How alpha-synuclein mutations cause Parkinson’s pathology
News highlights

How alpha-synuclein mutations cause Parkinson’s pathology

 5

New tool identifies drug targets to stop cancer treatment resistance
News highlights

New tool identifies drug targets to stop cancer treatm...

 8

News

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Controlling mitosis by cyclin-dependent kinase

Controlling mitosis by cyclin-dependent kinase

 22

Betaine as an exercise mimetic for aging protection

Betaine as an exercise mimetic for aging protection

 49

How immune cells fight – and are fooled by – malaria

How immune cells fight – and are fooled by – malaria

 43

Senescence-resistant human mesenchymal progenitor cells counter aging

Senescence-resistant human mesenchymal progenitor ...

 46

Fixing cholesterol metabolism problem to prevent blindness

Fixing cholesterol metabolism problem to prevent b...

 27

Predicting cognitive abilities from brain scans

Predicting cognitive abilities from brain scans

 32

GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity

GRK-biased adrenergic agonists for the treatment o...

 56

Oncogene mutation in colorectal cancer leads to metabolic reprogramming

Oncogene mutation in colorectal cancer leads to me...

 43

Alzheimer’s protective mutation works by taming inflammation in the brain

Alzheimer’s protective mutation works by taming in...

 52

An innovative drug for controlling weight and blood sugar

An innovative drug for controlling weight and bloo...

 114

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

 33

Switch-like gene expression modulates disease risk

Switch-like gene expression modulates disease risk

 40

How micronutrients taken up by our body

How micronutrients taken up by our body

 133

Meal-related memory in ventral hippocampus

Meal-related memory in ventral hippocampus

 23

Reward experience map in flexible hippocampal population

Reward experience map in flexible hippocampal popu...

 33

Neuroprosthesis for instantaneous voice-synthesis

Neuroprosthesis for instantaneous voice-synthesis

 51

ELAV protein shapes the brain’s unique circular RNA landscape

ELAV protein shapes the brain’s unique circular RN...

 60

Neurons associated with the suppression of binge drinking identified!

Neurons associated with the suppression of binge d...

 63

How the brain allows us to infer emotions

How the brain allows us to infer emotions

 43

How the brain forms habits and why they are so hard to break

How the brain forms habits and why they are so har...

 97

Molecular signatures of frontotemporal lobar degeneration

Molecular signatures of frontotemporal lobar degen...

 80

Impact of Alzheimer’s disease on the whole body

Impact of Alzheimer’s disease on the whole body

 97

How 2 proteins with opposite effect regulate huntingtin protein’s movement in neurons

How 2 proteins with opposite effect regulate hunti...

 55

Modulating synapses through astrocytes

Modulating synapses through astrocytes

 184

Dopamine D1–D2 signalling in hippocampus arbitrates approach and avoidance

Dopamine D1–D2 signalling in hippocampus arbitrate...

 136

Identical signature of unconsciousness with different anesthetics

Identical signature of unconsciousness with differ...

 95

Oncogene mutation in colorectal cancer leads to metabolic reprogramming

Oncogene mutation in colorectal cancer leads to me...

 43

HPV drives tumor development in rare nasal cancers

HPV drives tumor development in rare nasal cancers

 29

Tumor taurine drives glycolysis to promote leukaemogenesis

Tumor taurine drives glycolysis to promote leukaem...

 99

STAT5 and STAT3 balance shapes tumor immunity

STAT5 and STAT3 balance shapes tumor immunity

 109

Does brain cancer start at pregnancy?

Does brain cancer start at pregnancy?

 98

Zinc-transporting protein contributes to aggressive growth of brain tumor

Zinc-transporting protein contributes to aggressiv...

 136

Interplay between human genetics and intratumoral microbiota in colorectal cancer

Interplay between human genetics and intratumoral ...

 85

Ferroptosis induction by lysosomal lipid peroxidation

Ferroptosis induction by lysosomal lipid peroxidation

 182

Three-dimensional gene hubs may promote brain cancer

Three-dimensional gene hubs may promote brain cancer

 67

Targeting PIKfyve-driven lipid metabolism in pancreatic cancer

Targeting PIKfyve-driven lipid metabolism in pancr...

 89

Linking germline variants to cancer progression

Linking germline variants to cancer progression

 76

Tumor-derived erythropoietin acts as an immunosuppressive switch in cancer immunity

Tumor-derived erythropoietin acts as an immunosupp...

 168

Gut microbes release cancer-fighting bile acids that block hormone signals

Gut microbes release cancer-fighting bile acids th...

 229

GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity

GRK-biased adrenergic agonists for the treatment o...

 56

An innovative drug for controlling weight and blood sugar

An innovative drug for controlling weight and bloo...

 114

How maternal obesity also affects the next generation

How maternal obesity also affects the next generation

 41

A potential treatment for obesity-linked breathing disorder

A potential treatment for obesity-linked breathing...

 33

Tirzepatide's role in weight loss and metabolic health

Tirzepatide's role in weight loss and metabolic he...

 90

How molecular glues protect insulin-producing cells from diabetic damage

How molecular glues protect insulin-producing cell...

 168

Dramatic changes in liver metabolism during fasting

Dramatic changes in liver metabolism during fasting

 262

Obesity gene in dogs is also relevant to humans

Obesity gene in dogs is also relevant to humans

 177

Blood vessel inflammation from artificial sweetener

Blood vessel inflammation from artificial sweetener

 188

Adipose populations linked to metabolic health in obesity

Adipose populations linked to metabolic health in ...

 167

A light-sensitive brain protein, opsin 3, also regulates food consumption

A light-sensitive brain protein, opsin 3, also reg...

 211

Intermittent fasting could be unsafe for teenagers

Intermittent fasting could be unsafe for teenagers

 189

Mechanism of endothelial insulin resistance

Mechanism of endothelial insulin resistance

 198

Predicting cognitive abilities from brain scans

Predicting cognitive abilities from brain scans

 32

TACIT algorithm to diagnose and treat cancer

TACIT algorithm to diagnose and treat cancer

 33

N-acyl lipids in biology!

N-acyl lipids in biology!

 47

Generative AI to design RNA

Generative AI to design RNA

 73

How Type III CRISPR-Cas systems defend against viral infection?

How Type III CRISPR-Cas systems defend against vir...

 108

AI & imaging technique to evaluate blood clots in heart disease

AI & imaging technique to evaluate blood clots in ...

 73

AI to expand the mitochondrial targeting toolkit

AI to expand the mitochondrial targeting toolkit

 143

AI-powered app enables anemia screening using fingernail selfies

AI-powered app enables anemia screening using fing...

 62

Mapping centuries old genetic mutation that protects against HIV

Mapping centuries old genetic mutation that protec...

 79

AI uncovers antiviral compounds using limited data!

AI uncovers antiviral compounds using limited data!

 102

AI identifies PHGDH as amyloid pathology driver in Alzheimer’s disease

AI identifies PHGDH as amyloid pathology driver in...

 174

AI tool to better assess Parkinson’s disease, other movement disorders

AI tool to better assess Parkinson’s disease, othe...

 95

AI tool can track effectiveness of multiple sclerosis treatments

AI tool can track effectiveness of multiple sclero...

 96

Programmable gene insertion in human cells using a new gene editor

Programmable gene insertion in human cells using a...

 108

New lipid nanoparticle platform delivers mRNA to the brain through the blood-brain barrier

New lipid nanoparticle platform delivers mRNA to t...

 243

Microfluidic protocol to extract and purify DNA

Microfluidic protocol to extract and purify DNA

 136

Artificial sensing system using synthetic neurons

Artificial sensing system using synthetic neurons

 199

The nanoparticle-based vaccine against many variants of SARS-CoV-2

The nanoparticle-based vaccine against many varian...

 154

Nanoparticle-based itaconate treatment for atherosclerotic plaque resolution

Nanoparticle-based itaconate treatment for atheros...

 175

A lipid nanoparticle delivers mRNA cure for pre-eclampsia

A lipid nanoparticle delivers mRNA cure for pre-ec...

 172

‘Supercharging’ T cells with mitochondria enhances their antitumor activity

‘Supercharging’ T cells with mitochondria enhances...

 173

Can we ‘recharge’ our cells?

Can we ‘recharge’ our cells?

 183

Senescence-resistant human mesenchymal progenitor cells counter aging

Senescence-resistant human mesenchymal progenitor ...

 46

Glial replacement therapy slows Huntington’s disease

Glial replacement therapy slows Huntington’s disease

 50

A rapid method for building vascular organoids

A rapid method for building vascular organoids

 40

Platform for in vitro production of human microglia cells from iPSC

Platform for in vitro production of human microgli...

 69

How can alterations in metabolism encode specific transcriptional instructions

How can alterations in metabolism encode specific t...

 84

Growing chimpanzee naive-type pluripotent stem cells for the first time

Growing chimpanzee naive-type pluripotent stem cel...

 140

Aging-related blood disorders from supercharged mitochondria

Aging-related blood disorders from supercharged mi...

 112

New neurons may reverse damage in Huntington’s disease

New neurons may reverse damage in Huntington’s dis...

 105

Placenta-derived factor promotes the expansion of liver progenitor cells

Placenta-derived factor promotes the expansion of ...

 89

Human assembloid model of the ascending neural sensory pathway

Human assembloid model of the ascending neural sen...

 83

How gut cells respond to bacterial toxins

How gut cells respond to bacterial toxins

 276

Mechanisms of aging in Meibomian gland

Mechanisms of aging in Meibomian gland

 143

Stem cells based circadian drug delivery

Stem cells based circadian drug delivery

 139

ITSN1 gene linked to substantial risk of Parkinson’s disease

ITSN1 gene linked to substantial risk of Parkinson...

 135

Disordered renal metabolism in myotonic dystrophy type 1

Disordered renal metabolism in myotonic dystrophy ...

 134

Gene ‘silencer’ in junk DNA prevents fatal neurological disease

Gene ‘silencer’ in junk DNA prevents fatal neurolo...

 108

The role of moms X chromosome in cognition and aging of daughter

The role of moms X chromosome in cognition and agi...

 114

Genes for depression across ethnicities

Genes for depression across ethnicities

 134

Gene editing extends lifespan in mouse model of prion disease

Gene editing extends lifespan in mouse model of pr...

 112

Two new gene variants linked to epilepsy identified!

Two new gene variants linked to epilepsy identified!

 145

Dysregulation of mTOR signalling is a converging mechanism in lissencephaly

Dysregulation of mTOR signalling is a converging m...

 158

The role of rare germline structural variants in pediatric solid tumors

The role of rare germline structural variants in p...

 134

Linking genetic risk for schizophrenia to a malformed skull

Linking genetic risk for schizophrenia to a malfor...

 122

New mutation linked to early-onset Parkinsonism

New mutation linked to early-onset Parkinsonism

 153

Combination therapy to treat glioma

Combination therapy to treat glioma

 129

How unique metabolism protects naked mole rats from heart attacks

How unique metabolism protects naked mole rats fro...

 132

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

 160

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

 143

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

 145

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

 151

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

 139

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

 141

Role of ECM in brain memory

Role of ECM in brain memory

 136

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

 143

Supramolecular anticoagulants with on-demand reversibility

Supramolecular anticoagulants with on-demand rever...

 148

Cell vulnerability 'fingerprint' related to Parkinson's identified!

Cell vulnerability 'fingerprint' related to Parkin...

 144

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

 141

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

 132

Gut bacteria produced compounds can treat inflammation

Gut bacteria produced compounds can treat inflamma...

 135

Fixing cholesterol metabolism problem to prevent blindness

Fixing cholesterol metabolism problem to prevent b...

 27

Similarities between atherosclerotic blood vessels and tumor development

Similarities between atherosclerotic blood vessels...

 59

TMEM65 regulates mitochondrial calcium efflux

TMEM65 regulates mitochondrial calcium efflux

 92

Inhibition of ceramide synthesis contributes to cardiometabolic diseases

Inhibition of ceramide synthesis contributes to ca...

 86

How a Y chromosome gene may shape the course of heart valve disease

How a Y chromosome gene may shape the course of he...

 203

Why babies recover, but adults scar, after heart damage

Why babies recover, but adults scar, after heart d...

 114

Testosterone increases damage following a heart attack

Testosterone increases damage following a heart at...

 111

The structure of apolipoprotein B100 from human low-density lipoprotein

The structure of apolipoprotein B100 from human lo...

 131

Blood vessel lumen formation and maintenance

Blood vessel lumen formation and maintenance

 158

First noninvasive method to continually measure true blood pressure

First noninvasive method to continually measure tr...

 139

A glutamine metabolic switch in red blood cell development and disease

A glutamine metabolic switch in red blood cell dev...

 166

Protein kinase N promotes cardiac fibrosis in heart failure

Protein kinase N promotes cardiac fibrosis in hear...

 141

Role of lipids in regulating cardiac arrhythmias

Role of lipids in regulating cardiac arrhythmias

 192

High blood pressure in pregnancy linked to increased risk of seizure in children

High blood pressure in pregnancy linked to increas...

 41

Iron in sex determination of mammalian embryos

Iron in sex determination of mammalian embryos

 50

Temperature-controlled calcium channel, CatSper activates sperm

Temperature-controlled calcium channel, CatSper ac...

 80

How mothers adapt to the metabolic demands of nursing

How mothers adapt to the metabolic demands of nursing

 83

A protein complex critical to male fertility uncovered!

A protein complex critical to male fertility uncov...

 108

Association between placental DNA methylation and schizophrenia

Association between placental DNA methylation and ...

 491

Interactions between sex hormones and neurological health

Interactions between sex hormones and neurological...

 168

Cell-free DNA shed from the placenta during pregnancy predicts preeclampsia

Cell-free DNA shed from the placenta during pregna...

 139

Communication between body muscle and the brain influences fertility

Communication between body muscle and the brain in...

 152

Epigenetic programming in uterine fibroblasts regulate birth timing

Epigenetic programming in uterine fibroblasts regu...

 126

Grey matter (94%) in the brains of mothers undergoes changes during pregnancy

Grey matter (94%) in the brains of mothers undergo...

 134

Surges in estrogen promotes binge drinking in females

Surges in estrogen promotes binge drinking in females

 135

Extra X chromosome impairs the development of male fetal germ cells

Extra X chromosome impairs the development of male...

 154

Controlling mitosis by cyclin-dependent kinase

Controlling mitosis by cyclin-dependent kinase

 22

Switch-like gene expression modulates disease risk

Switch-like gene expression modulates disease risk

 40

Maintaining optimal pH within the Golgi apparatus

Maintaining optimal pH within the Golgi apparatus

 123

How cells untie DNA to protect the genome

How cells untie DNA to protect the genome

 37

Polysaccharide assembly and transport in Pseudomonas aeruginosa biofilm

Polysaccharide assembly and transport in Pseudomon...

 98

Reexamining binding determinants of a receptor linked to sepsis

Reexamining binding determinants of a receptor lin...

 42

How mRNA modification controls cellular stress response

How mRNA modification controls cellular stress res...

 342

A protein involved in autophagy of aggresomes identified!

A protein involved in autophagy of aggresomes iden...

 111

Eliminating excessive scarring during wound healing

Eliminating excessive scarring during wound healing

 100

Mechanism governing specific binding of EVs to recipient cells

Mechanism governing specific binding of EVs to rec...

 113

Circulating miR-126-3p is a biomarker for knee osteoarthritis

Circulating miR-126-3p is a biomarker for knee ost...

 90

Synthetic lethal interactions among DNA repair factors

Synthetic lethal interactions among DNA repair fac...

 67

Tool to analyze protein turnover in a single cell

Tool to analyze protein turnover in a single cell

 83

How immune cells fight – and are fooled by – malaria

How immune cells fight – and are fooled by – malaria

 43

Immune tolerance to gut microbes is initiated by a key bacterial sensor

Immune tolerance to gut microbes is initiated by a...

 55

New antibodies against current and future coronaviruses identified!

New antibodies against current and future coronavi...

 41

When bacteria get hungry, they kill – and eat – their neighbors

When bacteria get hungry, they kill – and eat – th...

 239

Jaundice-associated pigment in protecting against malaria

Jaundice-associated pigment in protecting against ...

 35

Bioenergetic trigger accelerating antibiotic resistance

Bioenergetic trigger accelerating antibiotic resis...

 38

How microbiota protects against influenza in newborns

How microbiota protects against influenza in newborns

 84

SARS-CoV-2 protein found to spread between cells, triggering immune attack on healthy cells

SARS-CoV-2 protein found to spread between cells, ...

 958

Lipid-based communication between body and gut microbes to maintain intestinal health

Lipid-based communication between body and gut mic...

 86

A new type of immune defense in E. coli

A new type of immune defense in E. coli

 85

A symbiotic gut fungus wards off liver disease in mice

A symbiotic gut fungus wards off liver disease in ...

 65

Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis

Nerve- and airway-associated interstitial macropha...

 115

First structural images of a tuberculosis-fighting virus

First structural images of a tuberculosis-fighting...

 120

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

 33

New stem cell model sheds light on human amniotic sac development

New stem cell model sheds light on human amniotic ...

 49

MicroRNAs guide the development of Purkinje cells

MicroRNAs guide the development of Purkinje cells

 156

Ancient viral DNA shapes early embryo development

Ancient viral DNA shapes early embryo development

 118

Mechanism to bring newborn neurons out of the neuronal nest

Mechanism to bring newborn neurons out of the neur...

 142

Leptin in neurodevelopment!

Leptin in neurodevelopment!

 146

Role of Integrator in early neural fate commitment

Role of Integrator in early neural fate commitment

 155

Impaired chaperonin function may cause brain malformations and seizures

Impaired chaperonin function may cause brain malfo...

 159

Role of protein netrin1 in spinal cord development

Role of protein netrin1 in spinal cord development

 139

Inhibiting metabolic enzyme to “pause" human development

Inhibiting metabolic enzyme to “pause" human devel...

 146

Human-specific genes regulate key gene mutated in autism spectrum disorders

Human-specific genes regulate key gene mutated in ...

 142

Physiological role of 5-formylcytosine (5fC) epigenetic marker in the embryonic development

Physiological role of 5-formylcytosine (5fC) epige...

 144

Mechanism of auxin influx in plants

Mechanism of auxin influx in plants

 60

Plant-based protein is linked to a longer life

Plant-based protein is linked to a longer life

 84

Epigenetic marker is essential for Marchantia sperm function

Epigenetic marker is essential for Marchantia sper...

 97

Anti-bacterial role of plant metabolite

Anti-bacterial role of plant metabolite

 133

Key genes to fight against crop parasites identified!

Key genes to fight against crop parasites identified!

 96

CoQ10-producing rice with gene editing

CoQ10-producing rice with gene editing

 111

Bacteria used to amplify plant hormones

Bacteria used to amplify plant hormones

 120

Protein protects biological nitrogen fixation from oxidative stress

Protein protects biological nitrogen fixation from...

 130

Plant roots change their growth pattern during ‘puberty’

Plant roots change their growth pattern during ‘pu...

 143

The biosynthesis of steroidal defense metabolites in plants

The biosynthesis of steroidal defense metabolites ...

 147

Decoding plant-to-fungi communication

Decoding plant-to-fungi communication

 156

Stopping plants from passing viruses to their progeny

Stopping plants from passing viruses to their progeny

 137

How female gametes control fertilization recovery in flowering plants

How female gametes control fertilization recovery ...

 146

Betaine as an exercise mimetic for aging protection

Betaine as an exercise mimetic for aging protection

 49

Alzheimer’s protective mutation works by taming inflammation in the brain

Alzheimer’s protective mutation works by taming in...

 52

Heterogeneity in immune cell abnormalities in patients with systemic sclerosis

Heterogeneity in immune cell abnormalities in pati...

 43

Why vaccination site matters for immune response

Why vaccination site matters for immune response

 188

Broadly neutralizing human antibodies to neutralize snake venom

Broadly neutralizing human antibodies to neutraliz...

 78

Lactate links metabolism and epigenetics for trained immunity

Lactate links metabolism and epigenetics for train...

 120

Predicting relapse of autoimmune small vessel vasculitis

Predicting relapse of autoimmune small vessel vasc...

 119

Asian Immune Diversity Atlas

Asian Immune Diversity Atlas

 62

Acetylcholine structure reveals mechanisms that cause autoimmune disease

Acetylcholine structure reveals mechanisms that ca...

 132

Peacekeeper cells protect the body from autoimmunity during infection

Peacekeeper cells protect the body from autoimmuni...

 238

Ginger compound with potential to treat inflammatory bowel disease

Ginger compound with potential to treat inflammato...

 129

Intercellular mRNA transfer alters the human pluripotent stem cell state

Intercellular mRNA transfer alters the human pluri...

 113

A treatment-resistant, severe type of asthma successfully modeled in mice

A treatment-resistant, severe type of asthma succe...

 100

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

 72

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

 68

Printed skin to replace animal testing

Printed skin to replace animal testing

 85

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

 92

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

 100

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

 111

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

 142

How micronutrients taken up by our body

How micronutrients taken up by our body

 133

Imaging-based STAMP technique for single-cell RNA analysis

Imaging-based STAMP technique for single-cell RNA ...

 32

Tracking the motions of GPCRs

Tracking the motions of GPCRs

 93

The structure of human sweetness

The structure of human sweetness

 114

Innovative deep-brain imaging to study brainstem structures

Innovative deep-brain imaging to study brainstem s...

 132

RNA blood test to detect cancers

RNA blood test to detect cancers

 103

EXPLORER total body PET scanner may help detect brain disease

EXPLORER total body PET scanner may help detect br...

 77

Simulating multilayered protein condensates support learning and memory

Simulating multilayered protein condensates suppor...

 88

Structural insight into mitochondrial pyruvate carrier

Structural insight into mitochondrial pyruvate car...

 96

Cell membranes sustain phospholipid imbalance via cholesterol asymmetry

Cell membranes sustain phospholipid imbalance via ...

 241

Nonlinear sound-sheet microscopy

Nonlinear sound-sheet microscopy

 90

Hearing triggered by molecular “spring”

Hearing triggered by molecular “spring”

 92

“Ball and chain” mechanism inactivates calcium-activated potassium channel

“Ball and chain” mechanism inactivates calcium-act...

 111

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

 34

How the brain regulates emotions

How the brain regulates emotions

 142

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

 130

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

 137

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

 160

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

 138

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

 153

Link between dietary choices and brain health

Link between dietary choices and brain health

 127

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

 156

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

 186

Males burn more fat, while females recycle it during exercise

Males burn more fat, while females recycle it duri...

 139

Paternal dietary macronutrient balance and energy intake drive metabolic and behavioral differences among offspring

Paternal dietary macronutrient balance and energy ...

 134

Research

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Emerging approaches to enhance human brain organoid physiology

Emerging approaches to enhance human brain organoi...

 31

Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition

Alpha-synuclein mutations mislocalize cytoplasmic ...

 37

Gene context drift identifies drug targets to mitigate cancer treatment resistance

Gene context drift identifies drug targets to miti...

 18

Spatiotemporal orchestration of mitosis by cyclin-dependent kinase

Spatiotemporal orchestration of mitosis by cyclin-...

 10

RIFINs displayed on malaria-infected erythrocytes bind KIR2DL1 and KIR2DS1

RIFINs displayed on malaria-infected erythrocytes ...

 22

Dysfunctional mitochondria trap proteins in the intermembrane space

Dysfunctional mitochondria trap proteins in the in...

 34

Gastric cancer: from biomarkers to functional precision medicine

Gastric cancer: from biomarkers to functional prec...

 62

The estrous cycle modulates hippocampal spine dynamics, dendritic processing, and spatial coding

The estrous cycle modulates hippocampal spine dyna...

 22

The gut microbiota promotes pain in fibromyalgia

The gut microbiota promotes pain in fibromyalgia

 33

Apolipoprotein M attenuates age-related macular degeneration phenotypes via sphingosine-1-phosphate signaling and lysosomal lipid catabolism

Apolipoprotein M attenuates age-related macular de...

 22

Rapid group-2 innate lymphoid cell mobilization from the intestine aids in early lung defense and repair

Rapid group-2 innate lymphoid cell mobilization fr...

 40

Immunotherapy-related cognitive impairment after CAR T cell therapy in mice

Immunotherapy-related cognitive impairment after C...

 41

Improving predictability, reliability, and generalizability of brain-wide associations for cognitive abilities via multimodal stacking

Improving predictability, reliability, and general...

 33

Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition

Alpha-synuclein mutations mislocalize cytoplasmic ...

 37

Spatiotemporal orchestration of mitosis by cyclin-dependent kinase

Spatiotemporal orchestration of mitosis by cyclin-...

 10

RIFINs displayed on malaria-infected erythrocytes bind KIR2DL1 and KIR2DS1

RIFINs displayed on malaria-infected erythrocytes ...

 22

Dysfunctional mitochondria trap proteins in the intermembrane space

Dysfunctional mitochondria trap proteins in the in...

 34

Gastric cancer: from biomarkers to functional precision medicine

Gastric cancer: from biomarkers to functional prec...

 62

The estrous cycle modulates hippocampal spine dynamics, dendritic processing, and spatial coding

The estrous cycle modulates hippocampal spine dyna...

 22

The gut microbiota promotes pain in fibromyalgia

The gut microbiota promotes pain in fibromyalgia

 33

Apolipoprotein M attenuates age-related macular degeneration phenotypes via sphingosine-1-phosphate signaling and lysosomal lipid catabolism

Apolipoprotein M attenuates age-related macular de...

 22

Rapid group-2 innate lymphoid cell mobilization from the intestine aids in early lung defense and repair

Rapid group-2 innate lymphoid cell mobilization fr...

 40

Immunotherapy-related cognitive impairment after CAR T cell therapy in mice

Immunotherapy-related cognitive impairment after C...

 41

GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity

GRK-biased adrenergic agonists for the treatment o...

 23

KRAS G12V mutation-selective requirement for ACSS2 in colorectal adenoma formation

KRAS G12V mutation-selective requirement for ACSS2...

 24

Fixed and flexible perceptual rhythms

Fixed and flexible perceptual rhythms

 20

Emerging approaches to enhance human brain organoid physiology

Emerging approaches to enhance human brain organoi...

 31

Gene context drift identifies drug targets to mitigate cancer treatment resistance

Gene context drift identifies drug targets to miti...

 18

Improving predictability, reliability, and generalizability of brain-wide associations for cognitive abilities via multimodal stacking

Improving predictability, reliability, and general...

 33

Glycine-to-aspartic acid mutation at codon 51 in Snca disrupts the synaptic localisation of α-synuclein and enhances its propensity for synucleinopathy

Glycine-to-aspartic acid mutation at codon 51 in S...

 33

Advancing nanopore technology toward protein identification and sequencing

Advancing nanopore technology toward protein ident...

 49

Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits

Enhancer AAV toolbox for accessing and perturbing ...

 43

Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC

Iterative transcription factor screening enables r...

 45

The microbiome diversifies long- to short-chain fatty acid-derived N-acyl lipids

The microbiome diversifies long- to short-chain fa...

 42

Generative and predictive neural networks for the design of functional RNA molecules

Generative and predictive neural networks for the ...

 57

An AAV capsid proposed as microglia-targeting directs genetic expression in forebrain excitatory neurons

An AAV capsid proposed as microglia-targeting dire...

 74

Minimally invasive, wide-field two-photon imaging of the brainstem at cellular resolution

Minimally invasive, wide-field two-photon imaging ...

 78

Quantitative PET imaging and modeling of molecular blood-brain barrier permeability

Quantitative PET imaging and modeling of molecular...

 88

Species-resolved profiling of antibiotic resistance genes in complex metagenomes through long-read overlapping with Argo

Species-resolved profiling of antibiotic resistanc...

 114

Anatomy of the Cerebellum

Anatomy of the Cerebellum

 99

Anatomy of the Hippocampus

Anatomy of the Hippocampus

 140

Cerebral Cortex

Cerebral Cortex

 129

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

 127

Protein Digestion and Absorption

Protein Digestion and Absorption

 547

AlphaFold: for Protein Structure Prediction

AlphaFold: for Protein Structure Prediction

 180

Protein structure, classification, functions, properties of proteins

Protein structure, classification, functions, prop...

 280

Post Translation Modification

Post Translation Modification

 293

Protein Translation

Protein Translation

 178

Transcription, Transcription Factors, and  Chromatin Remodeling

Transcription, Transcription Factors, and Chromat...

 279

AMINO ACIDS CLASSIFICATION  AND  PROPERTIES

AMINO ACIDS CLASSIFICATION AND PROPERTIES

 346

DNA replication

DNA replication

 212

DNA Repair

DNA Repair

 250

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

 9897

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

 382

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

 364

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

 390

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

 132

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

 122

HEAD AND NECK CANCER

HEAD AND NECK CANCER

 131

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

 125

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

 130

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

 135

School Science

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Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 100

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 111

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 111

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 281

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 217

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 145

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 151

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 132

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 161

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 136

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 161

APOE in Alzheimer’s

APOE in Alzheimer’s

 159

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 262

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 281

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 217

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 145

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 151

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 132

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 161

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 136

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 161

APOE in Alzheimer’s

APOE in Alzheimer’s

 159

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 262

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

 148

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

 172

Presenilin (PSEN)  in Alzheimer’s

Presenilin (PSEN)  in Alzheimer’s

 114

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 100

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 111

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 111

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